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Recombinant Human RhoB His Protein

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SDS-Page: Recombinant Human RhoB Protein [NBP1-72304] - 15% SDS-PAGE (3ug)
SDS-Page: Recombinant Human RhoB Protein [NBP1-72304] - 15% SDS-PAGE (3ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.25 mg/ml

Order Details

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Recombinant Human RhoB His Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-193 of Human RhoB

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAAIRKKLVV VGDGACGKTC LLIVFSKDEF PEVYVPTVFE NYVADIEVDG KQVELALWDT AGQEDYDRLR PLSYPDTDVI LMCFSVDSPD SLENIPEKWV PEVKHFCPNV PIILVANKKD LRSDEHVRTE LARMKQEPVR TDDGRAMAVR IQAYDYLECS AKTKEGVREV FETATRAALQ KRYGSQNGCI NCC

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
RHOB
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Dilutions
  • SDS-Page
Theoretical MW
23.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH 8.0), 2 mM DTT, 20% glycerol, 0.2 mM NaCl
Preservative
No Preservative
Concentration
0.25 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human RhoB His Protein

  • ARH6MSTP081
  • ARHBAplysia RAS-related homolog 6
  • h6
  • MST081
  • oncogene RHO H6
  • ras homolog gene family, member B
  • Rho cDNA clone 6
  • RHOH6RhoB
  • rho-related GTP-binding protein RhoB

Background

Rho-related GTP-binding protein RhoB, also known as RhoB, is a member of the Rho GTP-binding protein family. RhoB mediates apoptosis in neoplastically transformed cells after DNA damage. It plays a negative role in tumorigenesis as deletion causes tumor formation. Recombinant human RhoB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for RhoB Protein (NBP1-72304) (0)

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Research Areas for RhoB Protein (NBP1-72304)

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Blogs on RhoB.

Suppressing breast cancer metastasis: The role of hypoxia-induced RhoB expression and activation
By Jamshed Arslan, Pharm. D., PhD. The Ras homologous (Rho) GTPase family of signaling molecules has over 20 members, which typically cycle between active (GTP-bound) and inactive (GDP-bound) states. These small GTPa...  Read full blog post.

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Bioinformatics

Gene Symbol RHOB