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Ret Antibody (RET/2663) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, IHC, MA
Clone
RET/2663
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

Ret Antibody (RET/2663) [DyLight 405] Summary

Immunogen
Recombinant fragment (around aa 702-848) of human Ret protein (exact sequence is proprietary) (Uniprot: P07949)
Localization
Cytoplasmic, Cell Surface, Nuclear
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
RET
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Protein Array
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Ret Antibody (RET/2663) [DyLight 405]

  • CDHF12MTC1
  • CDHR16
  • EC 2.7.10
  • Hirschsprung disease 1
  • Hirschsprung disease)
  • MEN2A
  • MEN2B
  • multiple endocrine neoplasia and medullary thyroid carcinoma 1
  • ret proto-oncogene
  • RET transforming sequence
  • Ret

Background

Ret, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for Ret Antibody (NBP2-79896V) (0)

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Isotype Controls

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Bioinformatics

Gene Symbol RET