Recombinant Human IL-13 Protein

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells (1‑3). Mature human IL-13 shares approximately 58% amino acid sequence identity with mouse and rat IL-13. Despite the low homology, it exhibits cross‑species activity between human, mouse, and rat (4). IL-13 suppresses the production of proinflammatory cytokines and other cytotoxic substances by macrophages, fibroblasts, and endothelial cells. On B cells, it promotes cellular activation, immunoglobulin class switching to IgE, and the up‑regulation of CD23/Fc epsilon RII (1, 5). IL-13 binds with low affinity to the transmembrane IL-13 R alpha 1 which then forms a signaling complex with the transmembrane IL-4 R alpha (6‑8). This high affinity receptor complex also functions as the type 2 IL-4 receptor (6, 7). IL‑13 R alpha 2 inhibits responses to both IL-13 and IL-4. It binds IL-13 with high affinity (9, 10) and prevents IL-13 from signaling through the IL-13 R alpha 1/IL-4 R alpha complex (11, 12). It also blocks signaling through IL-4-occupied IL-13 R alpha 1/IL-4 R alpha receptor complexes (12, 13). In addition, IL-13-bound IL-13 R alpha 2 can directly promote tumor cell invasiveness and the development of tissue fibrosis (14‑16).

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 7 applications: Bioassay, Cell Culture, Differentiation, ELISA (Standard), Neutralization, Polarization, Stimulation.

Showing Publications 1 - 10 of 132. Show All 132 Publications. Collapse Publications.

Publications using 213-ILB	Applications	Species
Sasidharan, A;Grosche, A;Xu, X;Kinane, TB;Angoli, D;Vidyasagar, S; Select amino acids recover cytokine-altered ENaC function in human bronchial epithelial cells PloS one 2024-07-25 [PMID: 39052685] (Bioassay, Human)	Bioassay	Human
Bianconi, S;Leppik, L;Oppermann, E;Marzi, I;Henrich, D; Direct Current Electrical Stimulation Shifts THP-1-Derived Macrophage Polarization towards Pro-Regenerative M2 Phenotype International journal of molecular sciences 2024-07-02 [PMID: 39000377] (Bioassay, Human)	Bioassay	Human
Schmauch, E;Severin, Y;Xing, X;Mangold, A;Conrad, C;Johannsen, P;Kahlenberg, JM;Mellett, M;Navarini, A;Nobbe, S;Sarkar, MK;Satyam, A;Tsoi, LC;French, LE;Nilsson, J;Linna-Kuosmanen, S;Kaikkonen, MU;Snijder, B;Kellis, M;Gudjonsson, JE;Tsokos, GC;Contassot, E;Kolios, AGA; Targeting IL-1 controls refractory pityriasis rubra pilaris Science advances 2024-07-05 [PMID: 38959302] (Bioassay, Human)	Bioassay	Human
Brollo, M;Salvator, H;Grassin-Delyle, S;Glorion, M;Descamps, D;Buenestado, A;Naline, E;Tenor, H;Tiotiu, A;Devillier, P; The IL-4/13-induced production of M2 chemokines by human lung macrophages is enhanced by adenosine and PGE2 International immunopharmacology 2024-01-23 [PMID: 38266451] (Bioassay, Human)	Bioassay	Human
Hernandez, JD;Li, T;Ghannam, H;Rau, CM;Masuda, MY;Madura, JA;Jacobsen, EA;Filippis, E; Linking adipose tissue eosinophils, interleukin-4, and leptin in human obesity and insulin resistance JCI insight 2024-01-11 [PMID: 38206766] (Bioassay, Human)	Bioassay	Human
Liu, J;Deng, Y;Wang, A;Liu, B;Zhou, X;Yin, T;Wang, Y;Tang, T;Qiu, Y;Chen, J;Yang, J; Investigation into the role of the MITA-TRIM38 interaction in regulating pyroptosis and maintaining immune tolerance at the maternal-fetal interface Cell death & disease 2023-11-28 [PMID: 38012139] (Bioassay, Human)	Bioassay	Human
Katagata, M;Okayama, H;Nakajima, S;Saito, K;Sato, T;Sakuma, M;Fukai, S;Endo, E;Sakamoto, W;Saito, M;Saze, Z;Momma, T;Mimura, K;Kono, K; TIM-3 Expression and M2 Polarization of Macrophages in the TGF?-Activated Tumor Microenvironment in Colorectal Cancer Cancers 2023-10-11 [PMID: 37894310] (Cell Culture)	Cell Culture
Shuangshuang, H;Mengmeng, S;Lan, Z;Fang, Z;Yu, L; Maimendong decoction regulates M2 macrophage polarization to suppress pulmonary fibrosis via PI3K/Akt/FOXO3a signalling pathway-mediated fibroblast activation Journal of ethnopharmacology 2023-10-20 [PMID: 37865276] (Bioassay, Human)	Bioassay	Human
Gadde, M;Mehrabi-Dehdezi, M;Debeb, BG;Woodward, WA;Rylander, MN; Influence of Macrophages on Vascular Invasion of Inflammatory Breast Cancer Emboli Measured Using an In Vitro Microfluidic Multi-Cellular Platform Cancers 2023-10-08 [PMID: 37835577] (Bioassay, Human)	Bioassay	Human
Lu, J;Zhang, Q;Mo, L;Chen, W;Mao, L; Comprehensive analysis of E47?like factors and verification of ELF4 in clear cell renal cell carcinoma Oncology letters 2023-09-01 [PMID: 37600328] (Bioassay, Human)	Bioassay	Human
Raj, P;Paidi, S;Conway, L;Chatterjee, A;Barman, I; CellSNAP: A fast, accurate algorithm for 3D cell segmentation in quantitative phase imaging bioRxiv : the preprint server for biology 2023-08-13 [PMID: 37546926] (Bioassay, Human)	Bioassay	Human
Pan, HW;Guo, J;Zhu, L;Leung, SWS;Zhang, C;Lam, JKW; Enhanced powder dispersion of dual-excipient spray-dried powder formulations of a monoclonal antibody and its fragment for local treatment of severe asthma International journal of pharmaceutics 2023-07-25 [PMID: 37499774] (Bioassay, Human)	Bioassay	Human
Jing, Y;Mao, Z;Zhu, J;Ma, X;Liu, H;Chen, F; TRAIP serves as a potential prognostic biomarker and correlates with immune infiltrates in lung adenocarcinoma International immunopharmacology 2023-07-12 [PMID: 37451021] (Bioassay, Human)	Bioassay	Human
L Lerouge, M Gries, A Chateau, J Daouk, F Lux, P Rocchi, J Cedervall, AK Olsson, O Tillement, C Frochot, S Acherar, N Thomas, M Barberi-He Targeting Glioblastoma-Associated Macrophages for Photodynamic Therapy Using AGuIX�-Design Nanoparticles Pharmaceutics, 2023-03-20;15(3):. 2023-03-20 [PMID: 36986856] (Bioassay, Human)	Bioassay	Human
K Long, J Liu, S Shen, M Thong, D Wang, N Chen Light-sheet laser speckle imaging for cilia motility assessment Computational and structural biotechnology journal, 2023-02-20;21(0):1661-1669. 2023-02-20 [PMID: 36874161] (Bioassay, Human)	Bioassay	Human
CW Ku, J Yang, HY Tan, JKY Chan, YH Lee Decreased Innate Migration of Pro-Inflammatory M1 Macrophages through the Mesothelial Membrane Is Affected by Ceramide Kinase and Ceramide 1-P International Journal of Molecular Sciences, 2022-12-15;23(24):. 2022-12-15 [PMID: 36555618] (Polarization, Human)	Polarization	Human
R Akter, K Kim, HY Kwon, Y Kim, YW Eom, HM Cho, MY Cho EMR1/ADGRE1 Expression in Cancer Cells Upregulated by Tumor-Associated Macrophages Is Related to Poor Prognosis in Colorectal Cancer Biomedicines, 2022-12-02;10(12):. 2022-12-02 [PMID: 36551877] (Cell Culture, Human)	Cell Culture	Human
FH Wang, CY Hsieh, CI Shen, CH Chuang, YH Chung, CC Kuo, KD Lee, CL Lin, HL Su Induction of type II collagen expression in M2 macrophages derived from peripheral blood mononuclear cells Scientific Reports, 2022-12-15;12(1):21663. 2022-12-15 [PMID: 36522405] (Bioassay, Human)	Bioassay	Human
A Mentxaka, J Gómez-Ambr, B Ramírez, A Rodríguez, S Becerril, G Neira, V Valentí, R Moncada, C Silva, X Unamuno, JA Cienfuegos, J Escalada, G Frühbeck, V Catalán Netrin-1 Promotes Visceral Adipose Tissue Inflammation in Obesity and Is Associated with Insulin Resistance Nutrients, 2022-10-18;14(20):. 2022-10-18 [PMID: 36297056] (Cell Culture, Human)	Cell Culture	Human
F Real, A Zhu, B Huang, A Belmellat, A Sennepin, T Vogl, C Ransy, M Revol, R Arrigucci, A Lombès, J Roth, ML Gennaro, F Bouillaud, S Cristofari, M Bomsel S100A8-mediated metabolic adaptation controls HIV-1 persistence in macrophages in vivo Nature Communications, 2022-10-11;13(1):5956. 2022-10-11 [PMID: 36220814] (Bioassay, Human)	Bioassay	Human
H Cho, HY Kwon, A Sharma, SH Lee, X Liu, N Miyamoto, JJ Kim, SH Im, NY Kang, YT Chang Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target Nature Communications, 2022-10-10;13(1):5974. 2022-10-10 [PMID: 36216803] (Bioassay, Human)	Bioassay	Human
P Pavlidis, A Tsakmaki, A Treveil, K Li, D Cozzetto, F Yang, U Niazi, BH Hayee, M Saqi, J Friedman, T Korcsmaros, G Bewick, N Powell Cytokine responsive networks in human colonic epithelial organoids unveil a molecular classification of inflammatory bowel disease Cell Reports, 2022-09-27;40(13):111439. 2022-09-27 [PMID: 36170836] (Bioassay, Human)	Bioassay	Human
V Catalán, P Domench, J Gómez-Ambr, B Ramírez, S Becerril, A Mentxaka, A Rodríguez, V Valentí, R Moncada, J Baixauli, C Silva, J Escalada, G Frühbeck Dermatopontin Influences the Development of Obesity-Associated Colon Cancer by Changes in the Expression of Extracellular Matrix Proteins International Journal of Molecular Sciences, 2022-08-17;23(16):. 2022-08-17 [PMID: 36012487] (Stimulation, Human)	Stimulation	Human
S Segarra, T Naiken, J Garnier, V Hamon, N Coussay, FX Bernard Enhanced In Vitro Expression of Filaggrin and Antimicrobial Peptides Following Application of Glycosaminoglycans and a Sphingomyelin-Rich Lipid Extract Oncogene, 2022-06-27;9(7):. 2022-06-27 [PMID: 35878340] (Bioassay, Human)	Bioassay	Human
M Modak, AK Mattes, D Reiss, W Skronska-W, R Langlois, N Sabarth, R Konopitzky, F Ramírez, K Lehr, T Mayr, D Kind, C Viollet, LK Swee, J Petschenka, KC El Kasmi, E Noessner, K Kitt, S Pflanz CD206+ tumor-associated macrophages cross-present tumor antigen and drive anti-tumor immunity JCI Insight, 2022-06-08;0(0):. 2022-06-08 [PMID: 35503656] (Bioassay, Human)	Bioassay	Human
H Han, Y Kim, H Mo, SH Choi, K Lee, YA Rim, JH Ju Preferential stimulation of melanocytes by M2 macrophages to produce melanin through vascular endothelial growth factor Scientific Reports, 2022-04-19;12(1):6416. 2022-04-19 [PMID: 35440608] (Bioassay, Human)	Bioassay	Human
Y Imoto, S Ueki, Y Kato, K Yoshida, T Morikawa, Y Kimura, M Kidoguchi, T Tsutsumiuc, K Koyama, N Adachi, Y Ito, K Ogi, M Sakashita, T Yamada, RP Schleimer, T Takabayash, S Fujieda Elevated Serum Leptin Levels in Patients With Eosinophilic Chronic Rhinosinusitis Frontiers in Pharmacology, 2022-01-03;12(0):793607. 2022-01-03 [PMID: 35046816] (Bioassay, Human)	Bioassay	Human
A Kielczewsk, I D'Angelo, MS Amador, T Wang, A Sudom, X Min, P Rathanaswa, C Pigott, IN Foltz Development of a potent high-affinity human therapeutic antibody via novel application of Recombination Signal Sequence (RSS)-based Affinity Maturation The Journal of Biological Chemistry, 2021-12-29;0(0):101533. 2021-12-29 [PMID: 34973336] (Bioassay, Human)	Bioassay	Human
S Kim, HW Kim, SH Chang, KH Leem, HJ Park Bee Venom Prevents Mucin 5AC Production through Inhibition of AKT and SPDEF Activation in Airway Epithelia Cells Toxins, 2021-11-01;13(11):. 2021-11-01 [PMID: 34822557] (Bioassay, Human)	Bioassay	Human
E Kim, H Um, J Park, JW Jung, JE Kim, H Lee, EA Shin, Y Pinanga, H Lee, SH Nam, JW Lee TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment Cell Reports, 2021-11-16;37(7):110018. 2021-11-16 [PMID: 34788612] (Bioassay, Human)	Bioassay	Human
L Xiao, Y Shiwaku, R Hamai, K Tsuchiya, K Sasaki, O Suzuki Macrophage Polarization Related to Crystal Phases of Calcium Phosphate Biomaterials International Journal of Molecular Sciences, 2021-10-19;22(20):. 2021-10-19 [PMID: 34681912] (Polarization, Human)	Polarization	Human
A Kuzumi, A Yoshizaki, KM Matsuda, H Kotani, Y Norimatsu, M Fukayama, S Ebata, T Fukasawa, A Yoshizaki-, Y Asano, K Morikawa, Y Kazoe, K Mawatari, T Kitamori, S Sato Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis Nature Communications, 2021-10-12;12(1):5947. 2021-10-12 [PMID: 34642338] (Bioassay, Human)	Bioassay	Human
CN Noto, SG Hoft, KA Bockerstet, NM Jackson, EL Ford, LS Vest, RJ DiPaolo IL-13 acts directly on gastric epithelial cells to promote metaplasia development during chronic gastritis Cellular and Molecular Gastroenterology and Hepatology, 2021-09-26;0(0):. 2021-09-26 [PMID: 34587523] (Bioassay, Mouse)	Bioassay	Mouse
S Shao, J Chen, WR Swindell, LC Tsoi, X Xing, F Ma, R Uppala, MK Sarkar, O Plazyo, AC Billi, R Wasikowski, KM Smith, P Honore, VE Scott, E Maverakis, JM Kahlenberg, G Wang, NL Ward, PW Harms, JE Gudjonsson Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris JCI Insight, 2021-10-22;0(0):. 2021-10-22 [PMID: 34491907] (Bioassay, Human)	Bioassay	Human
I Gómez de S, P Ahechu, J Gómez-Ambr, A Rodríguez, B Ramírez, S Becerril, X Unamuno, A Mentxaka, J Baixauli, V Valentí, R Moncada, C Silva, G Frühbeck, V Catalán Decreased Levels of Microfibril-Associated Glycoprotein (MAGP)-1 in Patients with Colon Cancer and Obesity Are Associated with Changes in Extracellular Matrix Remodelling International Journal of Molecular Sciences, 2021-08-06;22(16):. 2021-08-06 [PMID: 34445187] (Bioassay, Human)	Bioassay	Human
B Jakiela, A Rebane, J Soja, S Bazan-Soch, A Laanesoo, H Plutecka, M Surmiak, M Sanak, K Sladek, G Bochenek Remodeling of bronchial epithelium caused by asthmatic inflammation affects its response to rhinovirus infection Scientific Reports, 2021-06-17;11(1):12821. 2021-06-17 [PMID: 34140575] (Cell Culture, Human)	Cell Culture	Human
X Huang, T Oshima, T Tomita, H Fukui, H Miwa Butyrate Alleviates Cytokine-Induced Barrier Dysfunction by Modifying Claudin-2 Levels Biology, 2021-03-09;10(3):. 2021-03-09 [PMID: 33803334] (Bioassay, Human)	Bioassay	Human
LB Richards, M Li, G Folkerts, PAJ Henricks, J Garssen, BCAM van Esch Butyrate and Propionate Restore the Cytokine and House Dust Mite Compromised Barrier Function of Human Bronchial Airway Epithelial Cells International Journal of Molecular Sciences, 2020-12-23;22(1):. 2020-12-23 [PMID: 33374733] (Bioassay, Human)	Bioassay	Human
T Wang, P Wang, D Chen, Z Xu, L Yang circARRDC3 contributes to interleukin?13?induced inflammatory cytokine and mucus production in nasal epithelial cells via the miR?375/KLF4 axis Molecular Medicine Reports, 2020-12-14;23(2):. 2020-12-14 [PMID: 33313951] (Cell Culture, Human)	Cell Culture	Human
I Hwang, JW Kim, K Ylaya, EJ Chung, H Kitano, C Perry, J Hanaoka, J Fukuoka, JY Chung, SM Hewitt Tumor-associated macrophage, angiogenesis and lymphangiogenesis markers predict prognosis of non-small cell lung cancer patients J Transl Med, 2020-11-23;18(1):443. 2020-11-23 [PMID: 33228719] (Cell Culture, Human)	Cell Culture	Human
HK Min, JY Won, BM Kim, KA Lee, SJ Lee, SH Lee, HR Kim, KW Kim Interleukin (IL)-25 suppresses IL-22-induced osteoclastogenesis in rheumatoid arthritis via STAT3 and p38 MAPK/I&kappaB&alpha pathway Arthritis Research & Therapy, 2020-09-23;22(1):222. 2020-09-23 [PMID: 32972460] (Human)		Human
X Yang, Q Guo, T Feng, Q Lu, L Ge, J Pan, K Bi, L Qiao, L Tian, T Xie, C Yao, G Song, L Wang IL13Ralpha1 protects against rheumatoid arthritis by combating the apoptotic resistance of fibroblast-like synoviocytes Arthritis Res. Ther., 2020-08-08;22(1):184. 2020-08-08 [PMID: 32771038] (Bioassay, Human)	Bioassay	Human
A Bulle, J Dekervel, L Deschutter, D Nittner, E Van Cutsem, C Verslype, J van Pelt Anti-Cancer Activity of Acriflavine as Metabolic Inhibitor of OXPHOS in Pancreas Cancer Xenografts Onco Targets Ther, 2020-07-15;13(0):6907-6916. 2020-07-15 [PMID: 32764982] (Bioassay, Human)	Bioassay	Human
KJ Gregory, SM Morin, A Kubosiak, J Ser-Dolans, B Schalet, DJ Jerry, SS Schneider The use of patient-derived breast tissue explants to study macrophage polarization and the effects of environmental chemical exposure Immunol. Cell Biol., 2020-09-09;0(0):. 2020-09-09 [PMID: 32713010] (Cell Culture, Human)	Cell Culture	Human
PF Duffney, HH Kim, NA Porter, I Jaspers Ozone-derived oxysterols impair lung macrophage phagocytosis via adduction of some phagocytosis receptors J. Biol. Chem., 2020-07-20;0(0):. 2020-07-20 [PMID: 32690608] (Cell Culture, Human)	Cell Culture	Human
ND Jackson, JL Everman, M Chioccioli, L Feriani, KC Goldfarbmu, SP Sajuthi, CL Rios, R Powell, M Armstrong, J Gomez, C Michel, C Eng, SS Oh, J Rodriguez-, P Cicuta, N Reisdorph, EG Burchard, MA Seibold Single-Cell and Population Transcriptomics Reveal Pan-epithelial Remodeling in Type 2-High Asthma Cell Rep, 2020-07-07;32(1):107872. 2020-07-07 [PMID: 32640237] (Cell Culture, Human)	Cell Culture	Human
J Yan, SP Pandey, BJ Barnes, JR Turner, C Abraham T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation Cell Rep, 2020-06-30;31(13):107820. 2020-06-30 [PMID: 32610123] (Bioassay, Human)	Bioassay	Human
Y Kubo, K Ishikawa, K Mori, Y Kobayashi, T Nakama, M Arima, S Nakao, T Hisatomi, M Haruta, KH Sonoda, S Yoshida Periostin and tenascin-C interaction promotes angiogenesis in ischemic proliferative retinopathy Sci Rep, 2020-06-09;10(1):9299. 2020-06-09 [PMID: 32518264] (Bioassay, Human)	Bioassay	Human
RA Lu, AA Zeki, S Ram-Mohan, N Nguyen, Y Bai, K Chmiel, S Pecic, X Ai, R Krishnan, CC Ghosh Inhibiting Airway Smooth Muscle Contraction Using Pitavastatin: A Role for the Mevalonate Pathway in Regulating Cytoskeletal Proteins Front Pharmacol, 2020-05-06;11(0):469. 2020-05-06 [PMID: 32435188] (Cell Culture, Human)	Cell Culture	Human
YD Kim, SM Park, HC Ha, AR Lee, H Won, H Cha, S Cho, JM Cho HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment J Cancer, 2020-04-06;11(14):4059-4072. 2020-04-06 [PMID: 32368288] (Bioassay, Human)	Bioassay	Human
X Unamuno, J Gómez-Ambr, B Ramírez, A Rodríguez, S Becerril, V Valentí, R Moncada, C Silva, J Salvador, G Frühbeck, V Catalán Dermatopontin, A Novel Adipokine Promoting Adipose Tissue Extracellular Matrix Remodelling and Inflammation in Obesity J Clin Med, 2020-04-09;9(4):. 2020-04-09 [PMID: 32283761] (Cell Culture, Human)	Cell Culture	Human
YJ Chen, CY Tsai, YM Cheng, SW Nieh, TK Yeh, CP Chen, MH Wang, LH Chou, TY Chiu, L Liu, C Ho, CT Chen, TW Liu Impacts of Intralipid on Nanodrug Abraxane Therapy and on the Innate Immune System Sci Rep, 2020-02-18;10(1):2838. 2020-02-18 [PMID: 32071352] (Cell Culture, Human)	Cell Culture	Human
YT Chang, HY Peng, CM Hu, SC Huang, SC Tien, YM Jeng Pancreatic cancer-derived small extracellular vesical Ezrin regulates macrophage polarization and promotes metastasis Am J Cancer Res, 2020-01-01;10(1):12-37. 2020-01-01 [PMID: 32064151] (Bioassay, Human)	Bioassay	Human
V Delprat, C Tellier, C Demazy, M Raes, O Feron, C Michiels Cycling hypoxia promotes a pro-inflammatory phenotype in macrophages via JNK/p65 signaling pathway Sci Rep, 2020-01-21;10(1):882. 2020-01-21 [PMID: 31964911] (Bioassay, Human)	Bioassay	Human
G Liu, L Yin, X Ouyang, K Zeng, Y Xiao, Y Li M2 Macrophages Promote HCC Cells Invasion and Migration via miR-149-5p/MMP9 Signaling J Cancer, 2020-01-01;11(5):1277-1287. 2020-01-01 [PMID: 31956374] (Cell Culture, Human)	Cell Culture	Human
SC Lee, MS Tang, AV Easton, JC Devlin, LL Chua, I Cho, FM Moy, TF Khang, YAL Lim, P Loke Linking the effects of helminth infection, diet and the gut microbiota with human whole-blood signatures PLoS Pathog., 2019-12-16;15(12):e1008066. 2019-12-16 [PMID: 31841569] (Cell Culture, Human)	Cell Culture	Human
SD Pauls, LA Rodway, T Winter, CG Taylor, P Zahradka, HM Aukema Alpha-linolenic acid enhances the phagocytic and secretory functions of alternatively activated macrophages in part via changes to the oxylipin profile Int. J. Biochem. Cell Biol., 2019-12-04;119(0):105662. 2019-12-04 [PMID: 31811954] (Bioassay, Human)	Bioassay	Human
N Berges, MS Nawaz, T Børresdatt, L Hagen, M Bjørås, JK Laerdahl, I Alseth Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform PLoS ONE, 2019-11-08;14(11):e0225081. 2019-11-08 [PMID: 31703097] (Cell Culture, Human)	Cell Culture	Human
X Unamuno, J Gómez-Ambr, B Ramírez, A Rodríguez, S Becerril, V Valentí, R Moncada, C Silva, J Salvador, G Frühbeck, V Catalán NLRP3 inflammasome blockade reduces adipose tissue inflammation and extracellular matrix remodeling Cell. Mol. Immunol., 2019-09-24;0(0):. 2019-09-24 [PMID: 31551515] (Bioassay, Human)	Bioassay	Human
Y Wu, MM Konaté, J Lu, H Makhlouf, R Chuaqui, S Antony, JL Meitzler, MJ Difilippan, H Liu, A Juhasz, G Jiang, I Dahan, K Roy, JH Doroshow IL-4 and IL-17A Cooperatively Promote Hydrogen Peroxide Production, Oxidative DNA Damage, and Upregulation of Dual Oxidase 2 in Human Colon and Pancreatic Cancer Cells J. Immunol., 2019-09-23;0(0):. 2019-09-23 [PMID: 31548328] (Bioassay, Human)	Bioassay	Human
S Sugihara, S Sugimoto, K Tachibana, M Kobashi, H Nomura, T Miyake, Y Hirai, O Yamasaki, S Morizane TNF-α and IL-17A induce the expression of lympho-epithelial Kazal-type inhibitor in epidermal keratinocytes J. Dermatol. Sci., 2019-08-21;0(0):. 2019-08-21 [PMID: 31501002] (Cell Culture, Human)	Cell Culture	Human
KJ Pahk, CH Shin, IY Bae, Y Yang, SH Kim, K Pahk, H Kim, SJ Oh Boiling Histotripsy-induced Partial Mechanical Ablation Modulates Tumour Microenvironment by Promoting Immunogenic Cell Death of Cancers Sci Rep, 2019-06-21;9(1):9050. 2019-06-21 [PMID: 31227775] (Bioassay, Human)	Bioassay	Human
X Qin, M Liu, S Zhang, C Wang, T Zhang The role of IL-36? and its regulation in eosinophilic inflammation in allergic rhinitis Cytokine, 2019-03-01;117(0):84-90. 2019-03-01 [PMID: 30831444] (Bioassay, Human)	Bioassay	Human
G Cantero-Re, CM Butnaru, N Brouwers, S Mitrovic, MA Valverde, V Malhotra Sodium channel TRPM4 and sodium/calcium exchangers (NCX) cooperate in the control of Ca2+-induced mucin secretion from goblet cells J. Biol. Chem., 2018-11-27;0(0):. 2018-11-27 [PMID: 30482841] (Bioassay, Human)	Bioassay	Human
L She, Y Qin, J Wang, C Liu, G Zhu, G Li, M Wei, C Chen, G Liu, D Zhang, X Chen, Y Wang, Y Qiu, Y Tian, X Zhang, Y Liu, D Huang Tumor-associated macrophages derived CCL18 promotes metastasis in squamous cell carcinoma of the head and neck Cancer Cell Int., 2018-08-28;18(0):120. 2018-08-28 [PMID: 30181713] (Bioassay, Human)	Bioassay	Human
SR Kim, JM Lewis, BM Cyrenne, PF Monico, FN Mirza, KR Carlson, FM Foss, M Girardi BET inhibition in advanced cutaneous T cell lymphoma is synergistically potentiated by BCL2 inhibition or HDAC inhibition Oncotarget, 2018-06-26;9(49):29193-29207. 2018-06-26 [PMID: 30018745] (Bioassay, Human)	Bioassay	Human
G Genard, AC Wera, C Huart, B Le Calve, S Penninckx, A Fattacciol, T Tabarrant, C Demazy, N Ninane, AC Heuskin, S Lucas, C Michiels Proton irradiation orchestrates macrophage reprogramming through NF?B signaling Cell Death Dis, 2018-06-27;9(7):728. 2018-06-27 [PMID: 29950610] (Bioassay, Human)	Bioassay	Human
I Pop?na, A ?bols, L Saul?te, K Pleiko, E Zandberga, K J?kabsons, E Endzeli?š, A Llorente, A Lin?, U Rieksti?a Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages Cell Commun. Signal, 2018-04-24;16(1):17. 2018-04-24 [PMID: 29690889] (Differentiation, Differentiation, Human)	Differentiation, Differentiation	Human
Y Ito, R Al Mubarak, N Roberts, K Correll, W Janssen, J Finigan, R Mishra, HW Chu IL-13 induces periostin and eotaxin expression in human primary alveolar epithelial cells: Comparison with paired airway epithelial cells PLoS ONE, 2018-04-19;13(4):e0196256. 2018-04-19 [PMID: 29672593] (Bioassay, Human)	Bioassay	Human
R da Silva A, AK Mehta, L Madge, J Tocker, M Croft TNFSF14 (LIGHT) Exhibits Inflammatory Activities in Lung Fibroblasts Complementary to IL-13 and TGF-β Front Immunol, 2018-03-19;9(0):576. 2018-03-19 [PMID: 29616048] (Cell Culture, Human)	Cell Culture	Human
EY Huang, JC Chang, HH Chen, CY Hsu, HC Hsu, KL Wu Carcinoembryonic antigen as a marker of radioresistance in colorectal cancer: a potential role of macrophages BMC Cancer, 2018-03-27;18(1):321. 2018-03-27 [PMID: 29580202] (Bioassay, Human)	Bioassay	Human
E Berdyshev, E Goleva, I Bronova, N Dyjack, C Rios, J Jung, P Taylor, M Jeong, CF Hall, BN Richers, KA Norquest, T Zheng, MA Seibold, DY Leung Lipid abnormalities in atopic skin are driven by type 2 cytokines JCI Insight, 2018-02-22;3(4):. 2018-02-22 [PMID: 29467325] (Bioassay, Human)	Bioassay	Human
M Gwiggner, RT Martinez-N, SR Whiteoak, VP Bondanese, A Claridge, JE Collins, JRF Cummings, T Sanchez-El MicroRNA-31 and MicroRNA-155 Are Overexpressed in Ulcerative Colitis and Regulate IL-13 Signaling by Targeting Interleukin 13 Receptor ?-1 Genes (Basel), 2018-02-13;9(2):. 2018-02-13 [PMID: 29438285] (Bioassay, Human)	Bioassay	Human
R Bruen, S Curley, S Kajani, D Crean, ME O'Reilly, MB Lucitt, CG Godson, FC McGillicud, O Belton Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis Cardiovasc Diabetol, 2017-11-06;16(1):143. 2017-11-06 [PMID: 29110715] (Bioassay, Human)	Bioassay	Human
Y Wang, JB Mumm, R Herbst, R Kolbeck, Y Wang IL-22 Increases Permeability of Intestinal Epithelial Tight Junctions by Enhancing Claudin-2 Expression J. Immunol., 2017-09-22;0(0):. 2017-09-22 [PMID: 28939759] (Bioassay, Human)	Bioassay	Human
J Zeitvogel, N Jokmin, S Rieker, I Klug, C Brandenber, T Werfel GATA3 regulates FLG and FLG2 expression in human primary keratinocytes Sci Rep, 2017-09-19;7(1):11847. 2017-09-19 [PMID: 28928464] (Bioassay, Human)	Bioassay	Human
S Bartel, N Schulz, F Alessandri, AC Schamberge, P Pagel, FJ Theis, K Milger, E Noessner, SM Stick, A Kicic, O Eickelberg, RJ Freishtat, S Krauss-Ets Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma Sci Rep, 2017-04-06;7(0):46026. 2017-04-06 [PMID: 28383034] (Bioassay, Human)	Bioassay	Human
T Nakama, S Yoshida, K Ishikawa, Y Kubo, Y Kobayashi, Y Zhou, S Nakao, T Hisatomi, Y Ikeda, K Takao, K Yoshikawa, A Matsuda, J Ono, S Ohta, K Izuhara, A Kudo, KH Sonoda, T Ishibashi Therapeutic Effect of Novel Single-Stranded RNAi Agent Targeting Periostin in Eyes with Retinal Neovascularization Mol Ther Nucleic Acids, 2017-02-09;6(0):279-289. 2017-02-09 [PMID: 28325294] (Bioassay, Human)	Bioassay	Human
BF Wang, PP Cao, ZC Wang, ZY Li, ZZ Wang, J Ma, B Liao, YK Deng, XB Long, K Xu, H Wang, H Wang, M Zeng, X Lu, Z Liu Interferon-? induced insufficient autophagy contributes to p62-dependent apoptosis of epithelial cells in chronic rhinosinusitis with nasal polyps Allergy, 2017-04-04;0(0):. 2017-04-04 [PMID: 28258963] (Bioassay, Human)	Bioassay	Human
J Ji, A Hedelin, M Malml”f, V Kessler, G Seisenbaev, P Gerde, L Palmberg Development of Combining of Human Bronchial Mucosa Models with XposeALI? for Exposure of Air Pollution Nanoparticles PLoS ONE, 2017-01-20;12(1):e0170428. 2017-01-20 [PMID: 28107509] (Bioassay, Human)	Bioassay	Human
B Popovic Structural Characterisation Reveals Mechanism of IL-13 Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13R?1 and IL-13R?2 J. Mol. Biol, 2016-12-09;0(0):. 2016-12-09 [PMID: 27956146] (Bioassay)	Bioassay
Leonardo J Galvão-Lim Classical and alternative macrophages have impaired function during acute and chronic HIV-1 infection Braz J Infect Dis, 2016-11-29;0(0):. 2016-11-29 [PMID: 27912071] (Bioassay, Human)	Bioassay	Human
Nathalie Castex-Riz Anti-inflammatory and immunomodulatory effects of Aquaphilus dolomiae extract on in vitro models Clin Cosmet Investig Dermatol, 2016-11-10;9(0):421-434. 2016-11-10 [PMID: 27877060] (Bioassay, Human)	Bioassay	Human
Thymic stromal chemokine TSLP acts through Th2 cytokine production to induce cutaneous T cell lymphoma Cancer Res, 2016-09-06;0(0):. 2016-09-06 [PMID: 27634769] (Bioassay, Human)	Bioassay	Human
Victoria Catalán Increased Interleukin-32 Levels in Obesity Promote Adipose Tissue Inflammation and Extracellular Matrix Remodeling: Effect of Weight Loss Diabetes, 2016-09-14;65(12):3636-3648. 2016-09-14 [PMID: 27630206] (Bioassay, Human)	Bioassay	Human
Edaire Cheng JAK-STAT6 Pathway Inhibitors Block Eotaxin-3 Secretion by Epithelial Cells and Fibroblasts from Esophageal Eosinophilia Patients: Promising Agents to Improve Inflammation and Prevent Fibrosis in EoE PLoS ONE, 2016-06-16;11(6):e0157376. 2016-06-16 [PMID: 27310888] (Bioassay, Human)	Bioassay	Human
S O'Reilly, M Ciechomska, N Fullard, S Przyborski, JM van Laar IL-13 mediates collagen deposition via STAT6 and microRNA-135b: a role for epigenetics Sci Rep, 2016-04-26;6(0):25066. 2016-04-26 [PMID: 27113293] (Bioassay, Human)	Bioassay	Human
Knight J, Mak G, Shaw J, Porter P, McDermott C, Roberts L, You R, Yuan X, Millien V, Qian Y, Song L, Frazier V, Kim C, Kim J, Bond R, Milner J, Zhang Y, Mandal P, Luong A, Kheradmand F, McMurray J, Corry D Long-Acting Beta Agonists Enhance Allergic Airway Disease. PLoS ONE, 2015-11-25;10(11):e0142212. 2015-11-25 [PMID: 26605551] (Bioassay, Human)	Bioassay	Human
Shipkowski K, Taylor A, Thompson E, Glista-Baker E, Sayers B, Messenger Z, Bauer R, Jaspers I, Bonner J An Allergic Lung Microenvironment Suppresses Carbon Nanotube-Induced Inflammasome Activation via STAT6-Dependent Inhibition of Caspase-1. PLoS ONE, 2015-06-19;10(6):e0128888. 2015-06-19 [PMID: 26091108] (Bioassay, Human)	Bioassay	Human
Lee J, Komatsu K, Lee B, Miyata M, O'Neill Bohn A, Xu H, Yan C, Li J Vinpocetine inhibits Streptococcus pneumoniae-induced upregulation of mucin MUC5AC expression via induction of MKP-1 phosphatase in the pathogenesis of otitis media. J Immunol, 2015-05-13;194(12):5990-8. 2015-05-13 [PMID: 25972475] (Bioassay, Human)	Bioassay	Human
Yao , Xiujuan, Wang , Wei, Li , Yan, Huang , Ping, Zhang , Qian, Wang , Jingjing, Wang , Wen, Lv , Zhe, An , Yunqing, Qin , Jianguo, Corrigan , Chris J, Huang , Kewu, Sun , Yongchan, Ying , Sun IL-25 induces airways angiogenesis and expression of multiple angiogenic factors in a murine asthma model. Respir Res, 2015-03-18;16(0):39. 2015-03-18 [PMID: 25889697] (Bioassay, Human)	Bioassay	Human
Kwofie K, Scott M, Rodrigues R, Guerette J, Radford K, Nair P, Richards C Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M. Respir Res, 2015-02-07;16(0):14. 2015-02-07 [PMID: 25849622] (Bioassay, Human)	Bioassay	Human
Xu J, Singhera G, Dorscheid D Expression of surfactant protein D in airways of asthmatics and interleukin-13 modulation of surfactant protein D in human models of airway epithelium. Respir Res, 2015-02-15;16(0):26. 2015-02-15 [PMID: 25848896] (Neutralization, Human)	Neutralization	Human
Zafra M, Canas J, Mazzeo C, Gamez C, Sanz V, Fernandez-Nieto M, Quirce S, Barranco P, Ruiz-Hornillos J, Sastre J, del Pozo V SOCS3 silencing attenuates eosinophil functions in asthma patients. Int J Mol Sci, 2015-03-10;16(3):5434-51. 2015-03-10 [PMID: 25764157] (Bioassay, Human)	Bioassay	Human
Herova M, Schmid M, Gemperle C, Hersberger M ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages. J Immunol, 2015-01-30;194(5):2330-7. 2015-01-30 [PMID: 25637017] (Bioassay, Human)	Bioassay	Human
Xie M, Mustovich A, Jiang Y, Trudeau J, Ray A, Ray P, Hu H, Holguin F, Freeman B, Wenzel S IL-27 and type 2 immunity in asthmatic patients: association with severity, CXCL9, and signal transducer and activator of transcription signaling. J Allergy Clin Immunol, 2014-10-11;135(2):386-94. 2014-10-11 [PMID: 25312760] (Bioassay, Human)	Bioassay	Human
Iwaisako K, Jiang C, Zhang M, Cong M, Moore-Morris T, Park T, Liu X, Xu J, Wang P, Paik Y, Meng F, Asagiri M, Murray L, Hofmann A, Iida T, Glass C, Brenner D, Kisseleva T Origin of myofibroblasts in the fibrotic liver in mice. Proc Natl Acad Sci U S A, 2014-07-29;111(32):E3297-305. 2014-07-29 [PMID: 25074909] (Bioassay, Human)	Bioassay	Human
Park , Jason Y, Zhang , Xi, Nguyen , Nathalie, Souza , Rhonda F, Spechler , Stuart J, Cheng , Edaire Proton pump inhibitors decrease eotaxin-3 expression in the proximal esophagus of children with esophageal eosinophilia. PLoS ONE, 2014-07-02;9(7):e101391. 2014-07-02 [PMID: 24988451] (Bioassay, Human)	Bioassay	Human
Melum G, Farkas L, Scheel C, Van Dieren B, Gran E, Liu Y, Johansen F, Jahnsen F, Baekkevold E A thymic stromal lymphopoietin-responsive dendritic cell subset mediates allergic responses in the upper airway mucosa. J Allergy Clin Immunol, 2014-06-21;134(3):613-621.e7. 2014-06-21 [PMID: 24958565] (Bioassay, Human)	Bioassay	Human
Voraphani N, Gladwin M, Contreras A, Kaminski N, Tedrow J, Milosevic J, Bleecker E, Meyers D, Ray A, Ray P, Erzurum S, Busse W, Zhao J, Trudeau J, Wenzel S An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe asthma. Mucosal Immunol, 2014-02-12;7(5):1175-85. 2014-02-12 [PMID: 24518246] (Bioassay, Human)	Bioassay	Human
Tanabe T, Shimokawaji T, Kanoh S, Rubin B IL-33 stimulates CXCL8/IL-8 secretion in goblet cells but not normally differentiated airway cells. Clin Exp Allergy, 2014-04-01;44(4):540-52. 2014-04-01 [PMID: 24479526] (Bioassay, Human)	Bioassay	Human
Ahmad T, Mukherjee S, Pattnaik B, Kumar M, Singh S, Kumar M, Rehman R, Tiwari B, Jha K, Barhanpurkar A, Wani M, Roy S, Mabalirajan U, Ghosh B, Agrawal A Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy. EMBO J, 2014-01-15;33(9):994-1010. 2014-01-15 [PMID: 24431222] (Bioassay, Human)	Bioassay	Human
Biancheri P, Di Sabatino A, Ammoscato F, Facciotti F, Caprioli F, Curciarello R, Hoque S, Ghanbari A, Joe-Njoku I, Giuffrida P, Rovedatti L, Geginat J, Corazza G, MacDonald T Absence of a role for interleukin-13 in inflammatory bowel disease. Eur J Immunol, 2014-02-01;44(2):370-85. 2014-02-01 [PMID: 24338958] (Bioassay, Human)	Bioassay	Human
Engstrom A, Erlandsson A, Delbro D, Wijkander J Conditioned media from macrophages of M1, but not M2 phenotype, inhibit the proliferation of the colon cancer cell lines HT-29 and CACO-2. Int J Oncol, 2013-12-02;44(2):385-92. 2013-12-02 [PMID: 24296981] (Bioassay, Human)	Bioassay	Human
Otsuka A, Doi H, Egawa G, Maekawa A, Fujita T, Nakamizo S, Nakashima C, Nakajima S, Watanabe T, Miyachi Y, Narumiya S, Kabashima K Possible new therapeutic strategy to regulate atopic dermatitis through upregulating filaggrin expression. J Allergy Clin Immunol, 2013-09-20;133(1):139-46.e1-10. 2013-09-20 [PMID: 24055295] (Bioassay, Human)	Bioassay	Human
Mabalirajan U, Rehman R, Ahmad T, Kumar S, Leishangthem G, Singh S, Dinda A, Biswal S, Agrawal A, Ghosh B 12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma. Sci Rep, 2013-01-01;3(0):1540. 2013-01-01 [PMID: 23528921] (Bioassay, Human)	Bioassay	Human
Pellerin L, Henry J, Hsu C, Balica S, Jean-Decoster C, Mechin M, Hansmann B, Rodriguez E, Weindinger S, Schmitt A, Serre G, Paul C, Simon M Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin. J Allergy Clin Immunol, 2013-02-10;131(4):1094-102. 2013-02-10 [PMID: 23403047] (Bioassay, Human)	Bioassay	Human
Gemperle C, Schmid M, Herova M, Marti-Jaun J, Wuest S, Loretz C, Hersberger M Regulation of the formyl peptide receptor 1 (FPR1) gene in primary human macrophages. PLoS ONE, 2012-11-21;7(11):e50195. 2012-11-21 [PMID: 23185575] (Bioassay, Human)	Bioassay	Human
Corvaisier M, Delneste Y, Jeanvoine H, Preisser L, Blanchard S, Garo E, Hoppe E, Barre B, Audran M, Bouvard B, Saint-Andre J, Jeannin P IL-26 Is Overexpressed in Rheumatoid Arthritis and Induces Proinflammatory Cytokine Production and Th17 Cell Generation. PLoS Biol, 2012-09-25;10(9):e1001395. 2012-09-25 [PMID: 23055831] (Bioassay, Human)	Bioassay	Human
Zhang J, Shan L, Koussih L, Redhu NS, Halayko AJ, Chakir J, Gounni AS Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production. PLoS ONE, 2012-04-18;7(4):e34965. 2012-04-18 [PMID: 22529962] (Bioassay, Human)	Bioassay	Human
Joubert P, Lajoie-Kadoch S, Wellemans V, Létuvé S, Tulic MK, Halayko AJ, Hamid Q Expression and regulation of CCL15 by human airway smooth muscle cells. Clin. Exp. Allergy, 2011-11-09;42(1):85-94. 2011-11-09 [PMID: 22092970] (Bioassay, Human)	Bioassay	Human
Epigenetic modulation enhances the therapeutic effect of anti-IL-13R alpha2 antibody in human mesothelioma xenografts. Clin. Cancer Res., 2011-02-28;17(9):2819-29. 2011-02-28 [PMID: 21357681] (Bioassay, Human)	Bioassay	Human
Le TA, Takai T, Kinoshita H, Suto H, Ikeda S, Okumura K, Ogawa H Inhibition of double-stranded RNA-induced TSLP in human keratinocytes by glucocorticoids. Allergy, 2009-03-27;64(8):1231-2. 2009-03-27 [PMID: 19416141] (Bioassay, Human)	Bioassay	Human
Ma P, Bian F, Wang Z, Zheng X, Chotikavanich S, Pflugfelder SC, Li DQ Human corneal epithelium-derived thymic stromal lymphopoietin links the innate and adaptive immune responses via TLRs and Th2 cytokines. Invest. Ophthalmol. Vis. Sci., 2009-01-17;50(6):2702-9. 2009-01-17 [PMID: 19151401] (Bioassay, Human)	Bioassay	Human
Eyerich K, Pennino D, Scarponi C, Foerster S, Nasorri F, Behrendt H, Ring J, Traidl-Hoffmann C, Albanesi C, Cavani A IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response. J. Allergy Clin. Immunol., 2008-12-03;123(1):59-66.e4. 2008-12-03 [PMID: 19056110] (Bioassay, Human)	Bioassay	Human
Mancino A, Schioppa T, Larghi P, Pasqualini F, Nebuloni M, Chen IH, Sozzani S, Austyn JM, Mantovani A, Sica A Divergent effects of hypoxia on dendritic cell functions. Blood, 2008-08-11;112(9):3723-34. 2008-08-11 [PMID: 18694997] (Bioassay, Human)	Bioassay	Human
Kato A, Peters A, Suh L, Carter R, Harris KE, Chandra R, Conley D, Grammer LC, Kern R, Schleimer RP Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps. J. Allergy Clin. Immunol., 2008-04-14;121(6):1385-92, 1392. 2008-04-14 [PMID: 18410958] (Bioassay, Human)	Bioassay	Human
Miller R, Sadhukhan R, Wu C Development of an in vitro potency bioassay for therapeutic IL-13 antagonists: the A-549 cell bioassay. J. Immunol. Methods, 2008-03-07;334(1):134-41. 2008-03-07 [PMID: 18355834] (Bioassay, Human)	Bioassay	Human
Liu TY, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, Ishihara O, Matsushita S Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells. Eur. J. Immunol., 2008-04-01;38(4):1012-23. 2008-04-01 [PMID: 18350544] (Bioassay, Human)	Bioassay	Human
Joubert P, Lajoie-Kadoch S, Welman M, Dragon S, Letuvee S, Tolloczko B, Halayko AJ, Gounni AS, Maghni K, Hamid Q Expression and regulation of CCR1 by airway smooth muscle cells in asthma. J. Immunol., 2008-01-15;180(2):1268-75. 2008-01-15 [PMID: 18178867] (Bioassay, Human)	Bioassay	Human
Kato A, Favoreto S, Avila PC, Schleimer RP TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells. J. Immunol., 2007-07-15;179(2):1080-7. 2007-07-15 [PMID: 17617600] (Bioassay, Human)	Bioassay	Human
Beisswenger C, Kandler K, Hess C, Garn H, Felgentreff K, Wegmann M, Renz H, Vogelmeier C, Bals R Allergic airway inflammation inhibits pulmonary antibacterial host defense. J. Immunol., 2006-08-01;177(3):1833-7. 2006-08-01 [PMID: 16849494] (Bioassay, Human)	Bioassay	Human
Howell MD, Gallo RL, Boguniewicz M, Jones JF, Wong C, Streib JE, Leung DY Cytokine milieu of atopic dermatitis skin subverts the innate immune response to vaccinia virus. Immunity, 2006-03-01;24(3):341-8. 2006-03-01 [PMID: 16546102] (Bioassay, Human)	Bioassay	Human
Baginski TK, Dabbagh K, Satjawatcharaphong C, Swinney DC Cigarette smoke synergistically enhances respiratory mucin induction by proinflammatory stimuli. Am. J. Respir. Cell Mol. Biol., 2006-03-16;35(2):165-74. 2006-03-16 [PMID: 16543607] (Bioassay, Human)	Bioassay	Human
Kiryushko D, Pavon L, Novitskaya V, Sandoval-Lopez G, Soroka V, Eugenia Hernandez M, Klingelhofer J, Loria F, Lukanidin E, Estrada I, Berezin V, Perez M, Bock E, Moreno J, Avila U, Leff P, Anton B, Heinze G Th2 cytokine response in Major Depressive Disorder patients before treatment. J. Neuroimmunol., 2006-02-02;172(1):156-65. 2006-02-02 [PMID: 16457895] (ELISA (Standard))	ELISA (Standard)
Fujitsu Y, Fukuda K, Kimura K, Seki K, Kumagai N, Nishida T Protection of human conjunctival fibroblasts from NO-induced apoptosis by interleukin-4 or interleukin-13. Invest. Ophthalmol. Vis. Sci., 2005-03-01;46(3):797-802. 2005-03-01 [PMID: 15728533] (Bioassay, Human)	Bioassay	Human
Kahlon KS, Brown C, Cooper LJ, Raubitschek A, Forman SJ, Jensen MC Specific recognition and killing of glioblastoma multiforme by interleukin 13-zetakine redirected cytolytic T cells. Cancer Res., 2004-12-15;64(24):9160-6. 2004-12-15 [PMID: 15604287] (Bioassay, Human)	Bioassay	Human
Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J. Immunol., 2004-09-01;173(5):3482-91. 2004-09-01 [PMID: 15322213] (Bioassay, Human)	Bioassay	Human
Kajiwara K, Shinazawa M, Morishima H, Yanagihara Y Differential effect of IL-4 and IL-13 on the expression of recombination-activating genes in mature B cells from human peripheral blood. Cell. Immunol., 2004-02-01;227(2):121-8. 2004-02-01 [PMID: 15135294] (Bioassay, Human)	Bioassay	Human
Bellinghausen I, Brand P, Bottcher I, Klostermann B, Knop J, Saloga J Production of interleukin-13 by human dendritic cells after stimulation with protein allergens is a key factor for induction of T helper 2 cytokines and is associated with activation of signal transducer and activator of transcription-6. Immunology, 2003-02-01;108(2):167-76. 2003-02-01 [PMID: 12562325] (Bioassay, Human)	Bioassay	Human
Schmid-Grendelmeier P, Altznauer F, Fischer B, Bizer C, Straumann A, Menz G, Blaser K, Wuthrich B, Simon HU Eosinophils express functional IL-13 in eosinophilic inflammatory diseases. J. Immunol., 2002-07-15;169(2):1021-7. 2002-07-15 [PMID: 12097410] (Bioassay, Human)	Bioassay	Human
Liu X, Kohyama T, Wang H, Zhu YK, Wen FQ, Kim HJ, Romberger DJ, Rennard SI Th2 cytokine regulation of type I collagen gel contraction mediated by human lung mesenchymal cells. Am. J. Physiol. Lung Cell Mol. Physiol., 2002-05-01;282(5):L1049-56. 2002-05-01 [PMID: 11943670] (Bioassay, Human)	Bioassay	Human
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Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	In vitro bioactivity in cell culture		06/09/2019	View Summary Application In vitro bioactivity in cell culture Lot DCSK0518041 Comments Cells supplied with 20ng/ml IL-4 and 100ng/ml of GM-CSF to differentiate dendritic cells
Enlarge	5 reviewed by: Verified Customer	CellProlif		10/07/2018	View Summary Application Cell Proliferation Lot DCSK0518041 Comments Comments Cells were supplied with the cytokinetreatments: 50 ng /ml GM-CSF and 10 ng/ ml1 of IL-13 to differentiate DC cells

Array 213-ILB

• IL-13 Antibodies
• IL-13 Antibody Pair
• IL-13 ELISA Kits
• IL-13 Lysate
• IL-13 Proteins
• IL-13 Proteins and Enzymes
• IL-13 ELISAs