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Niemann-Pick type C2 Antibody (012) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IP
Clone
012
Clonality
Monoclonal
Host
Rabbit
Conjugate
Janelia Fluor 585

Order Details

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Niemann-Pick type C2 Antibody (012) [Janelia Fluor® 585] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Human Niemann-Pick type C2 (Accession#: NP_006423.1; Met1-Leu151).
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
NPC2
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Niemann-Pick type C2 Antibody (012) [Janelia Fluor® 585]

  • EDDM1
  • Epididymal Protein 1
  • epididymal secretory protein E1
  • HE1
  • HE1epididymal protein 1
  • Human epididymis-specific protein 1
  • MGC1333
  • Niemann-Pick disease type C2 protein
  • Niemann-Pick disease, type C2
  • NiemannPick Type C2
  • Niemann-Pick Type C2
  • NPC2
  • NP-C2
  • tissue-specific secretory protein

Background

Niemann-Pick type C2 encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for Niemann-Pick type C2 Antibody (NBP2-90209JF585). (Showing 1 - 1 of 1 FAQ).

  1. I'm looking for a Niemann-Pick type1 or 2 antibody to stain mouse heart section embedded in paraffin. I would like to label these sections with another primary antibody to show colocalisation of my protein of interest. I would like to know if you have a rabbit anti-Niemann-Pick antibody that works well for fluorescence immunohistochemistry?
    • Niemann-Pick C1 Antibody (NB400-148) (0.1 ml) is one of our best sellers and this antibody has been cited in at least 17 peer reviewed research publications in journals of high repute. We have only one Niemann-Pick type C2 antibody with catalog # H00010577-D01PInnovators Reward Program.
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Bioinformatics

Gene Symbol NPC2