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IL-17RA/IL-17R Antibody (6Q2U9)

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Western Blot: IL-17RA/IL-17R Antibody (6Q2U9) [NBP3-16577] - Analysis of extracts of various cell lines, using IL-17RA/IL-17R Rabbit mAb (NBP3-16577) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG ...read more

Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB
Clone
6Q2U9
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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IL-17RA/IL-17R Antibody (6Q2U9) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 767-866 of human IL-17RA/IL-17R (Q96F46). GCSRPAMVLTDPHTPYEEEQRQSVQSDQGYISRSSPQPPEGLTEMEEEEEEEQDPGKPALPLSPEDLESLRSLQRQLLFRQLQKNSGWDTMGSESEGPSA
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
IL17RA
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500 -1:2000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS, 0.05% BSA, 50% glycerol, pH7.3
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for IL-17RA/IL-17R Antibody (6Q2U9)

  • CD217 antigen
  • CD217
  • Cdw217
  • CDw217interleukin 17 receptor
  • hIL-17R
  • IL-17 R
  • IL-17 RA
  • IL-17 receptor A
  • IL17RA
  • IL-17RA
  • IL-17RAMGC10262
  • IL17Rinterleukin-17 receptor A
  • interleukin 17 receptor A

Background

IL17RA is a gene that codes for a widely expressed protein that functions as a receptor for IL17A (a proinflammatory cytokine secreted by T-lymphocytes) with low affinity, which suggests that additional components are necessary to induce signaling and has a length of 866 amino acids and a weight of approximately 96 kDa. Current studies are being done on several diseases and disorders related to this gene including rheumatoid arthritis, cat eye syndrome, candidiasis, pituitary adenoma, bronchiolitis, cystic fibrosis, Sjogren's syndrome, keratitis, myocarditis, hepatitis B, liver disease, gingivitis, and osteoarthritis. IL17RA has also been shown to have interactions with IL17F, IL17RE, UBC, and TRAF3IP2 in pathways such as the IL-21 signaling, NF-kappaB signaling, and cytokine production pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IL17RA