Human IL-17C DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 6 of 6.

Publications using DY1234	Applications	Species
HJ Min, KS Kim IL-17C expression and its correlation with pediatric adenoids: a preliminary study International Journal of Medical Sciences, 2020-09-20;17(17):2603-2610. 2020-09-20 [PMID: 33162788] (Human)		Human
KC Jamieson, SL Traves, C Kooi, S Wiehler, CJ Dumonceaux, BA Maciejewsk, JW Arnason, AN Michi, R Leigh, D Proud Rhinovirus and Bacteria Synergistically Induce IL-17C Release from Human Airway Epithelial Cells To Promote Neutrophil Recruitment J. Immunol., 2018-11-30;0(0):. 2018-11-30 [PMID: 30504421] (Human)		Human
Johnston A, Fritz Y, Dawes S, Diaconu D, Al-Attar P, Guzman A, Chen C, Fu W, Gudjonsson J, McCormick T, Ward N Keratinocyte overexpression of IL-17C promotes psoriasiform skin inflammation. J Immunol, 2013-01-28;190(5):2252-62. 2013-01-28 [PMID: 23359500] (Human)		Human
Ramirez-Carrozzi V, Sambandam A, Luis E IL-17C regulates the innate immune function of epithelial cells in an autocrine manner. Nat. Immunol., 2011-10-12;12(12):1159-66. 2011-10-12 [PMID: 21993848] (Human)		Human
Johansen C, Riis JL, Gedebjerg A, Kragballe K, Iversen L Tumor necrosis factor alpha-mediated induction of interleukin 17C in human keratinocytes is controlled by nuclear factor kappaB. J. Biol. Chem., 2011-05-31;286(29):25487-94. 2011-05-31 [PMID: 21628458] (Human)		Human
Johansen C, Usher PA, Kjellerup RB Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin. Br. J. Dermatol., 2008-10-21;160(2):319-24. 2008-10-21 [PMID: 19016708] (Human)		Human

Array DY1234

• IL-17C Antibodies
• IL-17C Lysate
• IL-17C Protein
• IL-17C Proteins and Enzymes
• IL-17C ELISA