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Hexosaminidase A/HEXA Antibody (20F1) - BSA Free

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Western Blot: Hexosaminidase A/HEXA Antibody (20F1) [NBP2-42629] - Lane 1. 293T cell lysate, Lane 2. HEXA Transfected 293T cell lysate.
Western Blot: Hexosaminidase A/HEXA Antibody (20F1) [NBP2-42629] - Analysis in MCF7 lysates

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow
Clone
20F1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

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Hexosaminidase A/HEXA Antibody (20F1) - BSA Free Summary

Immunogen
Recombinant human Hexosaminidase A/HEXA (89-529aa) purified from E. coli
Isotype
IgG2a Lambda
Clonality
Monoclonal
Host
Mouse
Gene
HEXA
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Western Blot 1:3000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4), 10% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for Hexosaminidase A/HEXA Antibody (20F1) - BSA Free

  • beta-hexosaminidase subunit alpha
  • Beta-N-acetylhexosaminidase subunit alpha
  • EC 3.2.1
  • EC 3.2.1.52
  • HEXA
  • hexosaminidase A (alpha polypeptide)
  • Hexosaminidase A
  • Hexosaminidase subunit A
  • MGC99608
  • N-acetyl-beta-glucosaminidase subunit alpha
  • TSD

Background

HEXA encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol HEXA
Uniprot