Factor IX Antibody (2C9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using H00002158-M01	Applications	Species
Krooss S, Werwitzke S, Kopp J et al. Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant suppressing factor 9 RNA biogenesis leading to hemophilia B. PLoS Genet. 2020-04-08 [PMID: 32267853]

Array H00002158-M01

• Factor IX Antibodies
• Factor IX Antibody Pair
• Factor IX ELISA Kits
• Factor IX Lysate
• Factor IX Proteins and Enzyme