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CSE1L/CAS/Exportin-2 Antibody (2C10)

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Western Blot: CSE1L/CAS/Exportin-2 Antibody (2C10) [H00001434-M03] - Analysis of CSE1L expression in MCF-7 (Cat # L046V1).
Western Blot: CSE1L/CAS/Exportin-2 Antibody (2C10) [H00001434-M03] - Analysis of CSE1L expression in MCF-7 (Cat # L046V1).
Immunocytochemistry/ Immunofluorescence: CSE1L/CAS/Exportin-2 Antibody (2C10) [H00001434-M03] - Analysis of monoclonal antibody to CSE1L on HeLa cell. Antibody concentration 10 ug/ml
Immunohistochemistry-Paraffin: CSE1L/CAS/Exportin-2 Antibody (2C10) [H00001434-M03] - Analysis of monoclonal antibody to CSE1L on formalin-fixed paraffin-embedded human colon. Antibody concentration 3 ug/ml
ELISA: CSE1L/CAS/Exportin-2 Antibody (2C10) [H00001434-M03] - Detection limit for recombinant GST tagged CSE1L is approximately 0.3ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clone
2C10
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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CSE1L/CAS/Exportin-2 Antibody (2C10) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
CSE1L (NP_001307, 872 a.a. ~ 971 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LIGLFELPEDDTIPDEEHFIDIEDTPGYQTAFSQLAFAGKKEHDPVGQMVNNPKIHLAQSLHKLSTACPGRVPSMVSTSLNAEALQYLQGYLQAARVTLL
Specificity
CSE1L - CSE1 chromosome segregation 1-like (yeast)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CSE1L
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF, IHC-P and ELISA.
Publications
Read Publication using
H00001434-M03 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CSE1L/CAS/Exportin-2 Antibody (2C10)

  • CAS
  • CASMGC117283
  • Cellular apoptosis susceptibility protein
  • chromosome segregation 1 (yeast homolog)-like
  • Chromosome segregation 1-like protein
  • CSE1 chromosome segregation 1-like (yeast)
  • CSE1
  • CSE1L
  • exp2
  • exportin-2
  • Importin-alpha re-exporter
  • MGC130037
  • XPO2
  • XPO2MGC130036

Background

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CSE1L/CAS/Exportin-2 Antibody (H00001434-M03)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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Bioinformatics

Gene Symbol CSE1L
Entrez
OMIM
Uniprot