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CD8 beta Antibody (341) - Low Endotoxin and Azide Free

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Flow Cytometry: CD8 beta Antibody (341) - Low Endotoxin and Azide Free [NBP3-05298] - Separation of murine CD8b positive cells (red-filled) from CD8b negative cells (black-dashed) in flow cytometry analysis (surface staining) of murine splenocyte suspension stained using anti-rat CD8b (341) purified antibody (concentration in sample 1 ug/ml, GAM APC).
Flow Cytometry: CD8 beta Antibody (341) - Low Endotoxin and Azide Free [NBP3-05298] - Separation of murine CD8b positive cells (red-filled) from CD8b negative cells (black-dashed) in flow cytometry analysis (surface ...read more
Flow Cytometry: CD8 beta Antibody (341) - Low Endotoxin and Azide Free [NBP3-05298] - Surface staining pattern of rat splenocyte suspension stained using anti-rat CD8b (341) purified antibody (concentration in sample 1 ...read more

Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB, Flow, Func, IHC, IP
Clone
341
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Low Endotoxin and Azide Free
Concentration
1 mg/ml

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CD8 beta Antibody (341) - Low Endotoxin and Azide Free Summary

Immunogen
CD8 positive Wistar rat splenic T cell hybridomas
Specificity
The mouse monoclonal antibody 341 (also known as 34.1) recognizes rat CD8b, the 32-34 kDa beta chain of the CD8 coreceptor (extracellular epitope), expressed on T cell subsets and some other cell types, such as macrophages.
Clonality
Monoclonal
Host
Mouse
Gene
CD8B
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1-4 ug/ml
  • Functional
  • Immunohistochemistry-Frozen
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Phosphate buffered saline (PBS), pH 7.4
Preservative
No Preservative
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for CD8 beta Antibody (341) - Low Endotoxin and Azide Free

  • CD8 antigen, beta polypeptide 1 (p37)
  • CD8 beta
  • CD8b antigen
  • CD8b molecule
  • CD8b
  • CD8B1
  • CD8B1P37
  • Leu2
  • LY3
  • LYT3
  • MGC119115
  • P37
  • T lymphocyte surface glycoprotein beta chain
  • T-cell surface glycoprotein CD8 beta chain

Background

The H35-17.2 monoclonal antibody reacts with the mouse CD8beta molecule. The CD8beta chain associates with the CD8alpha chain to form the CD8alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alphabeta TCR T cells. CD8 binds to MHC class I and plays a role in T cell development and activation of mature T cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CD8B