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CD79A Antibody (HM57) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC
Clone
HM57
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 669

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-64347AF350
Alexa Fluor 405
NB100-64347AF405
Alexa Fluor 488
NB100-64347AF488
Alexa Fluor 532
NB100-64347AF532
Alexa Fluor 594
NB100-64347AF594
Alexa Fluor 647
NB100-64347AF647
Alexa Fluor 700
NB100-64347AF700
Alexa Fluor 750
NB100-64347AF750
Allophycocyanin
NB100-64347APC
Biotin
NB100-64347B
CoraFluor 1
NB100-64347CL1
DyLight 350
NB100-64347UV
DyLight 405
NB100-64347V
DyLight 488
NB100-64347G
DyLight 550
NB100-64347R
DyLight 594
NB100-64347DL594
DyLight 650
NB100-64347C
DyLight 680
NB100-64347FR
DyLight 755
NB100-64347IR
FITC
NB100-64347F
HRP
NB100-64347H
Janelia Fluor 525
NB100-64347JF525
Janelia Fluor 549
NB100-64347JF549
Janelia Fluor 585
NB100-64347JF585
Janelia Fluor 635
NB100-64347JF635
Janelia Fluor 646
NB100-64347JF646
PE
NB100-64347PE
PerCP
NB100-64347PCP
Unconjugated
NB100-64347
mFluor Violet 450 SE
NB100-64347MFV450
mFluor Violet 500 SE
NB100-64347MFV500
mFluor Violet 610 SE
NB100-64347MFV610
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CD79A Antibody (HM57) [Janelia Fluor® 669] Summary

Additional Information
Clone HM57 was used by HLDA to establish CD designation.
Immunogen
Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1
Specificity
NB100-64347 recognizes an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells. The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin. Clone HM57 has been reported to work in western blotting applications.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CD79A
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Cross reacts with Red Deer, Fallow Deer and American Bison. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for CD79A Antibody (HM57) [Janelia Fluor® 669]

  • CD79A antigen (immunoglobulin-associated alpha)
  • CD79a antigen
  • CD79a molecule, immunoglobulin-associated alpha
  • CD79A
  • IGAB-cell antigen receptor complex-associated protein alpha chain
  • ig-alpha
  • MB-1 membrane glycoprotein
  • MB1
  • MB-1
  • Membrane-bound immunoglobulin-associated protein
  • Surface IgM-associated protein

Background

CD79a is a disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CD79A