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CD-M6PR Antibody

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Chicken
Conjugate
Unconjugated

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CD-M6PR Antibody Summary

Immunogen
The immunogen for this antibody was a sequence from 60a.a. to 114a.a. from Mannose 6 Phosphate Receptor (Cation dependent)(a 277a.a. long protein)
Localization
Membrane; single-pass type I membrane protein.
Marker
Late Endosome Marker
Specificity
Mannose 6 Phosphate Receptor (Cation dependent)
Clonality
Polyclonal
Host
Chicken
Gene
M6PR
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:200 - 1:500
  • Western Blot 1:200 - 1:500
Application Notes
ICC: Immunocytochemistry staining of endogenous M6PR in normal rat kidney (NRK) cells. Affinity-Purified anti-M6PR IgY dilution: 1:200; Donkey anti-IgY Fc- FITC: 1:200.

Reactivity Notes

This antibody is reactive against Human, mouse, rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Notes

Chicken products cannot be exported to Canada.

Alternate Names for CD-M6PR Antibody

  • 000 Man6PR
  • 46 kDa mannose 6-phosphate receptor
  • 46-kDa mannose 6-phosphate receptor
  • cation-dependent mannose-6-phosphate receptor
  • CD Man-6-P receptor
  • CDM6PR
  • CD-M6PR
  • CD-MPR
  • FLJ32994
  • M6PR
  • mannose-6-phosphate receptor (cation dependent)
  • MPR 46
  • MPR46
  • MPRD
  • Mr 46
  • SMPR

Background

Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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ICC/IF Video Protocol

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Bioinformatics

Gene Symbol M6PR
Entrez
Uniprot