BDNF Antibody

FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Zebrafish.

We have publications tested in 7 applications: B/N, ICC/IF, IF/IHC, IHC, IHC-Fr, IHC-P, WB.

Showing Publications 1 - 10 of 34. Show All 34 Publications. Collapse Publications.

Publications using NB100-98682	Applications	Species
Gadsielinski M, Gladyszz D, Gralewski M Relationship between BDNF-positive number of nerve fibers and pain in intervertebral disc degeneration Sciforum 2023-01-01 (ICC/IF)	ICC/IF
Ma W, Wei X, Gu H et al. Intra-amniotic transplantation of brain-derived neurotrophic factor-modified mesenchymal stem cells treatment for rat fetuses with spina bifida aperta Stem cell research & therapy 2022-08-13 [PMID: 35964077] Details: Dilution used 1:25, Outbred Wistar rats
Doboszewska U, Socala K, PierOg M et al. The Effects and Mechanisms of Action of TC-G 1008, GPR39 Agonist, in Animal Models of Seizures and Epilepsy Cells 2022-07-09 [PMID: 35805072]
Saleem S, Banerjee R, Rajesh Kannan R Chrysin-Loaded Chitosan Nanoparticle-Mediated Neuroprotection in A beta 1-42-Induced Neurodegenerative Conditions in Zebrafish ACS chemical neuroscience 2022-06-13 [PMID: 35696319]
Fanarioti E, Tsarouchi M, Vasilakopoulou PB et al. Brain polar phenol content, behavioural and neurochemical effects of Corinthian currant in a rotenone rat model of Parkinson's disease Nutritional neuroscience 2022-06-03 [PMID: 35656969]
Pak M, Park y, yang H et al. Samhwangsasim-tang attenuates neuronal apoptosis and cognitive decline through BDNF-mediated activation of tyrosin kinase B and p75-neurotrophin receptors Phytomedicine 2022-02-01 [PMID: 35279612] (IF/IHC, Mouse)	IF/IHC	Mouse
Gentry N, McMahon T, Yamazaki M et al. Microglia are involved in the protection of memories formed during sleep deprivation Neurobiology of Sleep and Circadian Rhythms 2022-05-01 [PMID: 35028489] (WB, Mouse)	WB	Mouse
Wang J, Gao F, Cui S et al. Utility of 7,8-dihydroxyflavone in preventing astrocytic and synaptic deficits in the hippocampus elicited by PTSD Pharmacological research 2022-01-10 [PMID: 35026406] (WB, Mouse)	WB	Mouse
Topal A, Ozdemir S, Arslan H, Comakli S How does elevated water temperature affect fish brain? (A neurophysiological and experimental study: Assessment of brain derived neurotrophic factor, cFOS, apoptotic genes, heat shock genes, ER-stress genes and oxidative stress genes) Fish & shellfish immunology 2021-05-06 [PMID: 33965523]
Jung, D H, Ahn, S M Et al. Therapeutic effects of anodal transcranial direct current stimulation in a rat model of ADHD. Elife 2020-09-21 [PMID: 32955434] (ICC/IF, Mouse)	ICC/IF	Mouse
Wang X, Xu W, Chen H et al. Astragaloside IV prevents A beta 1-42 oligomers-induced memory impairment and hippocampal cell apoptosis by promoting PPAR gamma/BDNF signaling pathway Brain Res. 2020-07-30 [PMID: 32739157] (WB, Mouse)	WB	Mouse
Celik H, Kucukler S, Ozdemir S et al. Lycopene protects against central and peripheral neuropathy by inhibiting oxaliplatin-induced ATF-6 pathway, apoptosis, inflammation and oxidative stress in brains and sciatic tissues of rats Neurotoxicology 2020-06-13 [PMID: 32544411] (ICC/IF, WB, Rat)	ICC/IF, WB	Rat
Song Z, Shen F, Zhang Z et al. Calpain inhibition ameliorates depression-like behaviors by reducing inflammation and promoting synaptic protein expression in the hippocampus Neuropharmacology 2020-05-31 [PMID: 32492450] (WB, Mouse)	WB	Mouse
Ding H, Chen J, Su M et al. BDNF promotes activation of astrocytes and microglia contributing to neuroinflammation and mechanical allodynia in cyclophosphamide-induced cystitis J Neuroinflammation 2020-01-13 [PMID: 31931832] (WB, Rat)	WB	Rat
Kim Y R, Park B K et al. Antidepressant Effect of Fraxinus rhynchophylla Hance Extract in a Mouse Model of Chronic Stress-Induced Depression. Biomed Res Int 2018-02-08 [PMID: 30065945] (WB, IF/IHC, Mouse)	WB, IF/IHC	Mouse
Tikhonova, MA;Shvaikovskaya, AA;Zhanaeva, SY;Moysak, GI;Akopyan, AA;Rzaev, JA;Danilenko, KV;Aftanas, LI; Concordance between the In Vivo Content of Neurospecific Proteins (BDNF, NSE, VILIP-1, S100B) in the Hippocampus and Blood in Patients with Epilepsy International journal of molecular sciences 2023-12-29 [PMID: 38203674]
Gao Q, Gao Z, Su M et al. Umbilical Cord Mesenchymal Stem Cells Overexpressing Heme Oxygenase-1 Promotes Symptoms Recovery in Cystitis Rats by Alleviating Neuroinflammation Stem cells international 2023-11-14 [PMID: 38020203]
Filimonova EA, Pashkov AA, Moysak GI et al. Brain but not serum BDNF levels are associated with structural alterations in the hippocampal regions in patients with drug-resistant mesial temporal lobe epilepsy Frontiers in Neuroscience 2023-07-19 [PMID: 37539386] (IHC)	IHC
Poon CH, Liu Y, Pak S et al. Prelimbic Cortical Stimulation with L-methionine Enhances Cognition through Hippocampal DNA Methylation and Neuroplasticity Mechanisms Aging and disease 2023-02-01 [PMID: 36818556] (WB, Rat)	WB	Rat
Doboszewska U, Soca?a K, Pier�g M et al. Dietary Zinc Differentially Regulates the Effects of the GPR39 Receptor Agonist, TC-G 1008, in the Maximal Electroshock Seizure Test and Pentylenetetrazole-Kindling Model of Epilepsy Cells 2023-01-09 [PMID: 36672199] (B/N)	B/N
Staszkiewicz R, G?adysz D, Gralewski M et al. Usefulness of Detecting Brain-Derived Neurotrophic Factor in Intervertebral Disc Degeneration of the Lumbosacral Spine Medical science monitor : international medical journal of experimental and clinical research 2023-01-16 [PMID: 36642939] (IHC-Fr, Human) Details: 1:200 dilution	IHC-Fr	Human
Gao F, Wang J, Yang S et al. Fear extinction induced by activation of PKA ameliorates anxiety-like behavior in PTSD mice Neuropharmacology 2023-01-01 [PMID: 36341808] (WB, Mouse) Details: Dilution used in WB 1:1000	WB	Mouse
Ferguson L, Giza CC, Serpa RO et al. Sex Differences in Neurophysiological Changes Following Voluntary Exercise in Adolescent Rats Frontiers in Neurology 2021-07-22 [PMID: 34367052] (WB)	WB
Comakli S, Kokturk M, Topal A et al. Immunofluorescence/fluorescence assessment of brain-derived neurotrophic factor, c-Fos activation, and apoptosis in the brain of zebrafish (Danio rerio) larvae exposed to glufosinate. Neurotoxicology 2018-09-14 [PMID: 30222997] (IHC-P, Zebrafish)	IHC-P	Zebrafish
Kim Y, Park B, Kim Y et al. Antidepressant Effect of Fraxinus rhynchophylla Hance Extract in a Mouse Model of Chronic Stress-Induced Depression BioMed Research International 2018-07-03 [PMID: 30046601] (IF/IHC, Mouse)	IF/IHC	Mouse
Kim YR, Ahn SM, Pak ME, Lee HJ. Potential benefits of mesenchymal stem cells and electroacupuncture on the trophic factors associated with neurogenesis in mice with ischemic stroke. Sci Rep. 2018-02-01 [PMID: 29391466] (ICC/IF, Mouse)	ICC/IF	Mouse
Pak ME, Jung DH, Lee HJ et al. Combined therapy involving electroacupuncture and treadmill exercise attenuates demyelination in the corpus callosum by stimulating oligodendrogenesis in a rat model of neonatal hypoxia-ischemia. Exp. Neurol. 2018-02-01 [PMID: 29199131] (Rat)		Rat
Tang Y, Liu L, Xu D et al. Interaction between astrocytic colony stimulating factor and its receptor on microglia mediates central sensitization and behavioral hypersensitivity in chronic post ischemic pain model. Brain Behav Immun 2018-02-01 [PMID: 29080683]
Nam SM, Kim JW, Kwon HJ et al. Differential Effects of Low- and High-dose Zinc Supplementation on Synaptic Plasticity and Neurogenesis in the Hippocampus of Control and High-fat Diet-fed Mice Neurochem. Res. 2017-08-02 [PMID: 28770438] (WB, Mouse)	WB	Mouse
Lee HI, Lee SW, Kim NG et al. Low-level light emitting diode therapy promotes long-term functional recovery after experimental stroke in mice. J Biophotonics 2017-05-02 [PMID: 28464523] (Mouse) Details: The BDNF antibody was used to investigate the efficacy of using low level LED therapy in encouraging brain function recover of mice post stroke.		Mouse
Atasoy IL, Dursun E, Gezen-Ak D et al. Both secreted and the cellular levels of BDNF attenuated due to tau hyperphosphorylation in primary cultures of cortical neurons. J. Chem. Neuroanat. 2016-11-30 [PMID: 27914953] (ICC/IF, Rat)	ICC/IF	Rat
Efstathopoulos P, Kourgiantaki A, Karali K et al. Fingolimod induces neurogenesis in adult mouse hippocampus and improves contextual fear memory. Translational Psychiatry 2015-01-01 [PMID: 26795749] (WB, Mouse)	WB	Mouse
Show All 34 Publications. Collapse Publications.

Array NB100-98682

• BDNF Antibodies
• BDNF ELISA Kits
• BDNF Lysates
• BDNF Proteins
• BDNF ELISAs
• BDNF Proteins and Enzymes