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Aflatoxin B1 Antibody (6A10) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity Hu, AllSpecies Glossary
Applications WB, DB, ELISA, ICC/IF, IHC
Clone
6A10
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

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Aflatoxin B1 Antibody (6A10) [Janelia Fluor® 646] Summary

Immunogen
Aflatoxin B1 DNA (against the midazole ring-opened persistent form of the major N-7 guanine adduct of AFB1).
Localization
Nuclear
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Dot Blot
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Aflatoxin B1 Antibody (6A10) [Janelia Fluor® 646]

  • AFB1
  • AFB1-AR1
  • Aldoketoreductase 7

Background

Aflatoxin B1 is a naturally occurring mycotoxin produced by two types of mold: Aspergillus flavus and Aspergillus parasiticus. These molds commonly affect grains which are grown under stressful conditions such as drought and also grows on food that is stored in hot and humid conditions.

There are 13 known Aflatoxins produced, with aflatoxin B1 considered as the most toxic. In fact, Aflatoxin B1 is the most potent hepatocellular carcinoma (HCC) causing chemical currently known. Specifically, Aflatoxin B1 is thought to case mutations in the p53 gene which interfere with the gene's critical tumor suppressing functions.

Aflatoxin B1 are useful tools for studying hepatocellular carcinoma formation with wide ranging implications into public health and food saftey.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Aflatoxin B1 Antibody (NB600-443JF646) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for Aflatoxin B1 Antibody (NB600-443JF646)

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Blogs on Aflatoxin B1.

Using Aflatoxin B1 Antibody for Hepatocellular Carcinoma Studies
We at Novus Biologicals are constantly updating our antibody catalog in order to provide as comprehensive a database as possible for molecular biology researchers. Not all our antibodies are derived from proteins found in mammalian or human tissue. So...  Read full blog post.

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