Osteoprotegerin/TNFRSF11B Products

Description

Osteoprotegerin is encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq]

Bioinformatics

Uniprot	AAB53709 Human AAH30155 Human AAH30155.1 Human NP_002537 Human O00300 Human O14788 Human O14790 Human Q6PI12 Mouse
Product By Gene ID	4982
Alternate Names	OCIFMGC29565 OPG OPGtumor necrosis factor receptor superfamily member 11B Osteoclastogenesis inhibitory factor osteoprotegerin Osteoprotegerin TR1 tumor necrosis factor receptor superfamily, member 11b

Research Areas for Osteoprotegerin/TNFRSF11B

Find related products by research area and learn more about each of the different research areas below.

Apoptosis