L1CAM Products

Description

The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm.

Bioinformatics

Entrez	3897 Human
Uniprot	CAA42508 Human NM_000425 Human NP_000416 Human P32004 Human
Product By Gene ID	3897
Alternate Names	antigen identified by monoclonal R1 CAML1N-CAML1 CD171 antigen CD171 HSAS HSAS1 L1 cell adhesion molecule MASA MIC5 N-CAM-L1 NCAM-L1 neural cell adhesion molecule L1 S10 SPG1

Research Areas for L1CAM

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
Glia Markers
Neuroscience
Phospho-Specific

Related L1CAM Blog Posts

Check out the latest blog posts on L1CAM.

Identifying tumoral and stromal transcriptomes that underlie tumor plasticity and stromal neuroinflammatory response in brain metastasis By Jamshed Arslan, Pharm. D., PhD. Cancers in the brain often come from tumors elsewhere in the body. Several adaptive mechanisms influence brain metastasis, such as blood brain barrier leakage that can be induced by ...    Read more.

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