IL-2 Products

Description

Interleukin 2 (IL-2) is a potent immunoregulatory growth factor produced by T-cells following stimulation by mitogens or allogens. IL-2 promotes growth and differentiation of various cells of the immune system, such as activated T-cells and B-cells, NK cells, lymphokine activated killer cells, monocytes and macrophages. It is essential for proper immune response, it may also be an important factor in the natural suppression of autoimmunity. IL2 may be of use as an anti-tumor agent in cancer therapy. Recombinant human IL2 is a 15.5 kDa protein, consisting of 134 amino acid residues. Human and mouse IL-2 share 56% aa sequence identity and exhibit cross-species activity.

Bioinformatics

Entrez	116562 Rat 16183 Mouse 3558 Human
Uniprot	AAB46883 Human AAH66257.1 Human NM_000586 Human NP_000577 Human P04351 Mouse P60568 Human
Product By Gene ID	3558
Alternate Names	Aldesleukin aldesleukin IL-2 IL-2lymphokine interleukin 2 interleukin-2 involved in regulation of T-cell clonal expansion T cell growth factor T-cell growth factor TCGF

Research Areas for IL-2

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Biologically Active Proteins
Cytokine Research
Diabetes Research
Immunology
Innate Immunity
Mast Cell Markers

Related IL-2 Blog Posts

Check out the latest blog posts on IL-2.

The role of HIF-2 alpha in the progression and therapy of clear cell renal cell carcinoma HIF-2 alpha, also known as hypoxia-inducible factor 2, endothelial PAS domain protein-1, and member of PAS superfamily 2 is part of the HIF family of proteins.  The HIF family is composed of HIF-1, HIF-2 and HIF-3, where HIF-2 is a dimeric protein ...    Read more.

iNOS: The Nitric Oxide Boss Nitric oxide (NO) is an inorganic, gaseous, and reactive free radical that acts as a biologic mediator in processes such as neurotransmission, vasorelaxation, and cytotoxicity. In addition, it has antimicrobial and anti-tumoral activities. NO producti...    Read more.

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