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Human SLPI Quantikine ELISA Kit

 (36 Publications)
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Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Human SLPI Quantikine ELISA Kit Summary

Background
The Quantikine Human SLPI Immunoassay is a 4.5 hour solid phase ELISA designed to measure SLPI in cell culture supernates, serum, plasma, and urine. It contains E. coli-expressed recombinant human SLPI and antibodies raised against the recombinant factor. The kit has been shown to accurately quantitate recombinant human SLPI. Results obtained using natural human SLPI showed linear c...urves that were parallel to the curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural human SLPI.
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Specificity
Natural and recombinant human SLPI
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
SLPI

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DPI00.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human SLPI Quantikine ELISA Kit

  • ALK1
  • ALPProtease inhibitor WAP4
  • antileukoproteinase
  • BLPISeminal proteinase inhibitor
  • HUSI
  • HUSI-I
  • Mucus proteinase inhibitor
  • secretory leukocyte peptidase inhibitor
  • secretory leukocyte protease inhibitor (antileukoproteinase)
  • Secretory leukocyte protease inhibitor
  • SLPI
  • WAP four-disulfide core domain protein 4
  • WAP4HUSI-1
  • WFDC4MPI

Background

Secretory leukocyte protease inhibitor (SLPI) is found in various secretory fluids including parotid secretions, bronchial, nasal, cervical mucous, and seminal fluid. SLPI is a potent inhibitor of many proteolytic enzymes including the neutrophil proteases, elastase, cathepsin G, chymotrypsin, and trypsin.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for SLPI (DPI00)(36)

We have publications tested in 1 confirmed species: Human.


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Human
(36)
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Showing Publications 1 - 10 of 36. Show All 36 Publications.
Publications using DPI00 Applications Species
Knipping, K;Kartaram, SW;Teunis, M;Zuithoff, NPA;Buurman, N;M'Rabet, L;van Norren, K;Witkamp, R;Pieters, R;Garssen, J; Salivary concentrations of secretory leukocyte protease inhibitor and matrix metallopeptidase-9 following a single bout of exercise are associated with intensity and hydration status PloS one 2023-11-22 [PMID: 37992002] (Human) Human
Flerlage, T;Crawford, JC;Allen, EK;Severns, D;Tan, S;Surman, S;Ridout, G;Novak, T;Randolph, A;West, AN;Thomas, PG; Single cell transcriptomics identifies distinct profiles in pediatric acute respiratory distress syndrome Nature communications 2023-06-30 [PMID: 37391405] (Human) Human
Y Miyazaki, T Goto, X Li, K Nakayama, K Okasho, M Takeda, K Mizuno, H Kimura, M Uegaki, T Sumiyoshi, Y Teramoto, S Akamatsu, T Kobayashi, O Ogawa, T Inoue Up-regulation of secretory leukocyte protease inhibitor in human samples might have a potential role of predicting prostate cancer recurrence and progression after surgery and hormonal therapy Cancer Medicine, 2022-08-13;12(3):3328-3342. 2022-08-13 [PMID: 36812122] (Human) Human
KT Sawicki, DR Nannini, SJ Bielinski, NB Larson, DM Lloyd-Jone, B Psaty, KD Taylor, SJ Shah, LJ Rasmussen-, JT Wilkins, EM McNally, RB Patel Secretory leukocyte protease inhibitor and risk of heart failure in the Multi-Ethnic Study of Atherosclerosis Scientific Reports, 2023-01-12;13(1):604. 2023-01-12 [PMID: 36635319] (Human) Human
DL Frey, C Bridson, S Dittrich, SY Graeber, M Stahl, S Wege, F Herth, O Sommerburg, C Schultz, A Dalpke, MA Mall, S Boutin Changes in Microbiome Dominance Are Associated With Declining Lung Function and Fluctuating Inflammation in People With Cystic Fibrosis Frontiers in Microbiology, 2022-05-13;13(0):885822. 2022-05-13 [PMID: 35633718] (Human) Human
O Sibila, L Perea, N Albacar, J Moisés, T Cruz, N Mendoza, B Solarat, G Lledó, G Espinosa, JA Barberà, JR Badia, A Agustí, J Sellarés, R Faner Elevated plasma levels of epithelial and endothelial cell markers in COVID-19 survivors with reduced lung diffusing capacity six months after hospital discharge Respiratory Research, 2022-02-21;23(1):37. 2022-02-21 [PMID: 35189887] (Human) Human
BL Dickey, B Sirak, L Martin-Gom, RR Reich, M Abrahamsen, K Isaacs-Sor, CH Chung, AR Giuliano Oral secretory leukocyte protease inhibitor (SLPI): Associations with oropharyngeal cancer and treatment outcome PLoS ONE, 2021-07-02;16(7):e0254161. 2021-07-02 [PMID: 34214131] (Human) Human
T Samejima, T Nagamatsu, N Akiba, T Fujii, S Sayama, K Kawana, A Taguchi, K Kumasawa, T Iriyama, Y Osuga, T Fujii Secretory leukocyte protease inhibitor and progranulin as possible regulators of cervical remodeling in pregnancy J Reprod Immunol, 2020-11-01;143(0):103241. 2020-11-01 [PMID: 33157500] (Human) Human
A Stanton, C Mowbray, M Lanz, K Brown, P Hilton, A Tyson-Capp, RS Pickard, ASM Ali, J Hall Topical Estrogen Treatment Augments the Vaginal Response to Escherichia coli Flagellin Sci Rep, 2020-05-21;10(1):8473. 2020-05-21 [PMID: 32439855] (Human) Human
HJ Whitwell, J Worthingto, O Blyuss, A Gentry-Mah, A Ryan, R Gunu, J Kalsi, U Menon, I Jacobs, A Zaikin, JF Timms Improved early detection of ovarian cancer using longitudinal multimarker models Br. J. Cancer, 2020-01-15;0(0):. 2020-01-15 [PMID: 31937926] (Human) Human
Show All 36 Publications.

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Bioinformatics

Gene Symbol SLPI