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Hyperargininemia: Disease Bioinformatics

Research of Hyperargininemia has been linked to Hyperammonemia, Urea Cycle Disorders, Inborn, Ornithine Carbamoyltransferase Deficiency, Inborn Errors Of Metabolism, Argininosuccinic Aciduria. The study of Hyperargininemia has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Hyperargininemia include Urea Cycle, Excretion, Pathogenesis, Transport, Immune Response. These pathways complement our catalog of research reagents for the study of Hyperargininemia including antibodies and ELISA kits against OTC, ASS1, ARG1, ARGINASE I, AI.

Top Research Reagents

We have 1656 products for the study of Hyperargininemia that can be applied to Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NB300-605
Western Blot: iNOS Antibody [NB300-605] - Analysis of iNOS was performed by loading 20 ug of RAW264 whole cell lysate untreated (left lane) or stimulated with LPS at 1 ug/mL for 16 hours (right lane) and 10 uL of PageRuler Plus Prestained Protein Ladder onto a 4-20% Tris-Glycine polyacrylamide gel. Proteins were transferred to a nitrocellulose membrane and blocked with 5% Milk in TBST for at least 1 hour. The membrane was probed with an iNOS Rabbit polyclonal antibody at a dilution of 1:1000 overnight at 4C on a rocking platform, washed in TBST, and probed with a Goat anti-Rabbit IgG (H+L) Secondary Antibody, HRP conjugate at a dilution of 1:1000 for 1 hour. Chemiluminescent detection was performed using SuperSignal West Pico.Immunohistochemistry-Paraffin: iNOS Antibody [NB300-605] - Immunohistochemistry was performed on normal deparaffinized human Lung tissue.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, IB

     3 Reviews

130 Publications
NBP1-32731
Knockdown Validated: Arginase 1/ARG1/liver Arginase Antibody [NBP1-32731] - Non-transfected (-) and transfected (+) HepG2 whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Arginase 1 antibody.Immunohistochemistry: Arginase 1/ARG1/liver Arginase Antibody [NBP1-32731] - TRP53-regulated EndMT modulates the M1 and M2 populations of increased TAMs after radiotherapy. Immunofluorescence detection of F4/80, CD31, and Arg1, in KP tumours from WT and EC-p53KO mice, with or without irradiation (23 days after irradiation). Image collected and cropped by Citeab from the following publication (Tumour-vasculature development via endothelial-to-mesenchymal transition after radiotherapy controls CD44v6+ cancer cell and macrophage polarization. Nat Commun (2018) licensed under a CC-BY license.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, Flow

     1 Review

24 Publications
NBP1-87408
Immunohistochemistry-Paraffin: Ornithine Carbamoyltransferase Antibody [NBP1-87408] - Staining in human liver and kidney tissues . Corresponding OTC RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: Ornithine Carbamoyltransferase Antibody [NBP1-87408] - Staining of human cerebral cortex, kidney, liver and small intestine using Anti-OTC antibody NBP1-87408 (A) shows similar protein distribution across tissues to independent antibody NBP1-88121 (B).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Simple Western, ICC/IF

5 Publications
NBP1-87462
Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462] - Staining in human liver and skeletal muscle tissues using NBP1-87462 antibody. Corresponding ASL RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: Argininosuccinate Lyase Antibody [NBP1-87462] - Staining of human kidney shows moderate to strong cytoplasmic positivity in cells in tubules.

Rabbit Polyclonal
Species Human, Canine
Applications WB, IHC, IHC-P

2 Publications
NBP1-88868
Western Blot: Argininosuccinate Synthase Antibody [NBP1-88868] - ASS1 was successfully silenced in H4-II-E-C3 cells. Image from verified customer review.Immunocytochemistry/Immunofluorescence: Argininosuccinate Synthase Antibody [NBP1-88868] - Staining of human cell line A-431 shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

     1 Review

NBP1-89290
Immunohistochemistry-Paraffin: ACADS Antibody [NBP1-89290] - Analysis in human duodenum and tonsil tissues. Corresponding ACADS RNA-seq data are presented for the same tissues.Western Blot: ACADS Antibody [NBP1-89290] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)<br/>Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP1-89342
Immunohistochemistry-Paraffin: ATP6V0A1 Antibody [NBP1-89342] - Analysis in human cerebral cortex and tonsil tissues. Corresponding ATP6V0A1 RNA-seq data are presented for the same tissues.Western Blot: ATP6V0A1 Antibody [NBP1-89342] - In Cln1-/- mice V0a1 is misrouted to plasma membrane preventing its interaction with AP-3. Pull-down assay with AP-3 antibody using total lysates from untreated (lane 1) and bromopalmitate-treated (lane 2) WT brain slices to detect V0a1 and its densitometric quantitation (n=4, *P<0.05). HEK-293 cells were transfected with WT GFP-V0a1 and GFP-V0a1-Cys25Ser mutant construct, and pull-down experiments were conducted with AP-3 antibody to detect GFP-V0a1,*P<0.05(n=4). Image collected and cropped by CiteAb from the following publication (https://www.nature.com/doifinder/10.1038/ncomms14612), licensed under a CC-BY license.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

     1 Review

13 Publications
MAB7185
Western blot shows lysates of human placenta tissue and human kidney tissue. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human TINAGL1 Monoclonal Antibody (Catalog # MAB7185) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <a class=Simple Western lane view shows lysates of human placenta tissue, loaded at 0.5 mg/mL. A specific band was detected for TINAGL1 at approximately 59 kDa (as indicated) using 5 µg/mL of Mouse Anti-Human TINAGL1 Monoclonal Antibody (Catalog # MAB7185). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system. </P><P>Non-specific interaction with the 230 kDa Simple Western standard may be seen with this antibody.

Mouse Monoclonal
Species Human
Applications WB, Simple Western

AF6457
Western blot shows lysates of Daudi human Burkitt's lymphoma cell line. Gels were loaded with 30 µg of whole cell lysate (WCL), 20 µg of cytoplasmic (Cyto), and 10 µg of nuclear extracts (Nuc). PVDF Membrane was probed with 1 µg/mL of Sheep Anti-Human RFC1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6457) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <a class=

Sheep Polyclonal
Species Human
Applications WB

7954-GM/CF
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED<sub>50</sub> for this effect is 6-30 pg/mL.


Species Human
Applications BA

3 Publications
NBP2-42388
Immunohistochemistry-Paraffin: LAMC2 Antibody (CL2980) [NBP2-42388] - Staining in human fallopian tube and liver tissues. Corresponding LAMC2 RNA-seq data are presented for the same tissues.Western Blot: LAMC2 Antibody (CL2980) [NBP2-42388] - Analysis in A-431 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-LAMC2 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

4 Publications
NBP2-45946
Western Blot: RFC4 Antibody (OTI1A8) [NBP2-45946] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RFC4.Immunocytochemistry/Immunofluorescence: RFC4 Antibody (OTI1A8) [NBP2-45946] - Analysis  of COS7 cells transiently transfected by pCMV6-ENTRY RFC4.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NBP2-46539
Western Blot: ARG2 Antibody (OTI3G5) [NBP2-46539] - Analysis of extracts (10ug) from 3 different mouse tissues, dilution (1:200).Immunocytochemistry/Immunofluorescence: ARG2 Antibody (OTI3G5) [NBP2-46539] - ARG2 Antibody (3G5) [NBP2-46539] - Analysis  of COS7 cells transiently transfected by pCMV6-ENTRY ARG2.

Mouse Monoclonal
Species Human, Rat, Canine
Applications WB, ICC/IF, IHC

NBP2-73857
Western Blot: RFC2 Antibody (OTI2B2) - Azide and BSA Free [NBP2-73857] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RFC2.Immunohistochemistry: RFC2 Antibody (OTI2B2) - Azide and BSA Free [NBP2-73857] - Analysis of Human prostate tissue.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, IHC

NB100-858
Immunocytochemistry/Immunofluorescence: nNOS Antibody [NB100-858] - Action potentials were evoked with depolarizing current pulses. (A) Neuron from colonic specimen of non-treated patient fired 1 action potential in response to a depolarizing current. (A') Intracellular injection of carboxyfluorescein during recording confirmed Dogiel type I, uniaxonal morphology. (AImmunohistochemistry-Paraffin: nNOS Antibody [NB100-858] - Staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Antibody at 2.5 ug/mL.

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

     1 Review

15 Publications
NBP2-93763
Western Blot: NAGS Antibody [NBP2-93763] - Analysis of extracts of various cell lines, using NAGS at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA


Related PTMs

Hyperargininemia has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Hyperargininemia is also known as hyperargininemia, argininemia, arginase deficiency (disorder), deficiency of canavanase, malnutrition.