Name: Contactin-1 Antibody [Unconjugated]
Brand: Novus Biologicals
SKU: AF904
Price: 489 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	Hu, Mu, RtSpecies Glossary
Applications	WB, Simple Western, IHC, B/N
Clonality	Polyclonal
Host	Goat
Conjugate	Unconjugated
Concentration	LYOPH

Conjugate	Catalog #	Availability	Size	Price
Biotin	BAF904

Immunogen	S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Contactin-1 Glu21-Ser993 Accession # CAA79696
Specificity	Detects human Contactin-1 in direct ELISAs. Detects human, mouse, and rat Contactin-1 in Western blots.
Source	N/A
Isotype	IgG
Clonality	Polyclonal
Host	Goat
Gene	CNTN1
Purity Statement	Antigen Affinity-purified
Endotoxin Note	<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.2 mg/mL in sterile PBS.

Contactin-1 Antibody [Unconjugated]

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Publications for Contactin-1 Antibody (AF904)(21)

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Bioinformatics

Publications using AF904	Applications	Species
Ogawa, Y;Lim, BC;George, S;Oses-Prieto, JA;Rasband, JM;Eshed-Eisenbach, Y;Hamdan, H;Nair, S;Boato, F;Peles, E;Burlingame, AL;Van Aelst, L;Rasband, MN; Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments Nature communications 2023-10-26 [PMID: 37884508] (ICC, Rat)	ICC	Rat
Guillaume Taieb, Alexandre Jentzer, Elisa Vegezzi, Cinta Lleixà, Isabel Illa, Luis Querol et al. Effect of monovalency on anti-contactin-1 IgG4 Frontiers in Immunology 2023-03-14 [PMID: 36999029]
Y Ogawa, BC Lim, S George, JA Oses-Priet, JM Rasband, Y Eshed-Eise, S Nair, F Boato, E Peles, AL Burlingame, LV Aelst, MN Rasband Antibody-directed extracellular proximity biotinylation reveals Contactin-1 regulates axo-axonic innervation of axon initial segments bioRxiv : the preprint server for biology, 2023-03-06;0(0):. 2023-03-06 [PMID: 36945454] (ICC, Rat)	ICC	Rat
J Fehmi, AJ Davies, M Antonelou, S Keddie, S Pikkupeura, L Querol, E Delmont, A Cortese, D Franciotta, S Persson, J Barratt, R Pepper, F Farinha, A Rahman, D Canetti, JA Gilbertson, NB Rendell, A Radunovic, T Minton, G Fuller, SM Murphy, AS Carr, MR Reilly, F Eftimov, L Wieske, CE Teunissen, ISD Roberts, N Ashman, AD Salama, S Rinaldi Contactin-1 links autoimmune neuropathy and membranous glomerulonephritis PLoS ONE, 2023-03-09;18(3):e0281156. 3/9/2023 [PMID: 36893151]
Cifuentes-Diaz C, Canali G, Garcia M et al. Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse Frontiers in Neuroscience 2023-01-30 [PMID: 36793543]
R Kuwayama, K Suzuki, J Nakamura, E Aizawa, Y Yoshioka, M Ikawa, S Nabatame, KI Inoue, Y Shimmyo, K Ozono, T Kinoshita, Y Murakami Establishment of mouse model of inherited PIGO deficiency and therapeutic potential of AAV-based gene therapy Nature Communications, 2022-06-03;13(1):3107. 2022-06-03 [PMID: 35661110] (Western Blot, Mouse)	Western Blot	Mouse
KJ Chang, I Agrawal, A Vainshtein, WY Ho, W Xin, G Tucker-Kel, K Susuki, E Peles, SC Ling, JR Chan TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells Elife, 2021-03-10;10(0):. 2021-03-10 [PMID: 33689679] (IHC, Mouse)	IHC	Mouse
Estelle Lecluze, Antoine D Rolland, Panagiotis Filis, Bertrand Evrard, Sabrina Leverrier-Penna, Millissia Ben Maamar et al. Dynamics of the transcriptional landscape during human fetal testis and ovary development Human Reproduction 2020-05-01 [PMID: 32412604]
C Manso, L Querol, C Lleixà, M Poncelet, M Mekaouche, JM Vallat, I Illa, JJ Devaux Anti-Neurofascin-155 IgG4 antibodies prevent paranodal complex formation in vivo J. Clin. Invest., 2019-03-14;130(0):. 2019-03-14 [PMID: 30869655] (ICC, Human)	ICC	Human
A Stojic, J Bojcevski, SK Williams, R Diem, R Fairless Early Nodal and Paranodal Disruption in Autoimmune Optic Neuritis J. Neuropathol. Exp. Neurol., 2018-05-01;0(0):. 2018-05-01 [PMID: 29444299] (Western Blot, Rat)	Western Blot	Rat
L Montani, JA Pereira, C Norrmén, HBF Pohl, E Tinelli, M Trötzmülle, G Figlia, P Dimas, B von Nieder, R Schwager, S Jessberger, CF Semenkovic, HC Köfeler, U Suter De novo fatty acid synthesis by Schwann cells is essential for peripheral nervous system myelination J. Cell Biol., 2018-02-06;0(0):. 2018-02-06 [PMID: 29434029] (IHC, Mouse)	IHC	Mouse
L Querol, AM Siles, R Alba-Rovir, A Jáuregui, J Devaux, C Faivre-Sar, J Araque, R Rojas-Garc, J Diaz-Maner, E Cortés-Vic, G Nogales-Ga, M Navas-Madr, E Gallardo, I Illa Antibodies against peripheral nerve antigens in chronic inflammatory demyelinating polyradiculoneuropathy Sci Rep, 2017-10-31;7(1):14411. 2017-10-31 [PMID: 29089585] (ICC, Human)	ICC	Human
Pierre-Marie Martin Schwannomin-interacting protein 1 isoform IQCJ-SCHIP1 is a multi-partner ankyrin and spectrin binding protein involved in the organization of nodes of Ranvier J. Biol. Chem, 2016-12-15;0(0):. 2016-12-15 [PMID: 27979964] (IHC, Mouse)	IHC	Mouse
Kae-Jiun Chang, Daniel R. Zollinger, Keiichiro Susuki, Diane L. Sherman, Michael A. Makara, Peter J. Brophy et al. Glial ankyrins facilitate paranodal axoglial junction assembly Nature Neuroscience 2014-12-01 [PMID: 25362471]
Colakoglu G, Bergstrom-Tyrberg U, Berglund E, Ranscht B Contactin-1 regulates myelination and nodal/paranodal domain organization in the central nervous system. Proc Natl Acad Sci U S A, 2014-01-02;111(3):E394-403. 2014-01-02 [PMID: 24385581] (Western Blot, Mouse)	Western Blot	Mouse
Tian N, Leshchyns'ka I, Welch J, Diakowski W, Yang H, Schachner M, Sytnyk V Lipid raft-dependent endocytosis of close homolog of adhesion molecule L1 (CHL1) promotes neuritogenesis. J Biol Chem, 2012-11-09;287(53):44447-63. 2012-11-09 [PMID: 23144456] (Western Blot, Mouse)	Western Blot	Mouse
Muriel T. Davisson, Roderick T. Bronson, Abigail L. D. Tadenev, William W. Motley, Arjun Krishnaswamy, Kevin L. Seburn et al. A Spontaneous Mutation in Contactin 1 in the Mouse PLoS ONE 2011-12-29 [PMID: 22242131]
Dours-Zimmermann MT, Maurer K, Rauch U, Stoffel W, Fassler R, Zimmermann DR Versican V2 assembles the extracellular matrix surrounding the nodes of ranvier in the CNS. J. Neurosci., 2009-06-17;29(24):7731-42. 2009-06-17 [PMID: 19535585] (IHC, Mouse)	IHC	Mouse
Lieberoth A, Splittstoesser F, Katagihallimath N, Jakovcevski I, Loers G, Ranscht B, Karagogeos D, Schachner M, Kleene R Lewis(x) and alpha2,3-sialyl glycans and their receptors TAG-1, Contactin, and L1 mediate CD24-dependent neurite outgrowth. J. Neurosci., 2009-05-20;29(20):6677-90. 2009-05-20 [PMID: 19458237] (ICC, Immunoprecipitation, Neutralization, Mouse)	ICC, Immunoprecipitation, Neutralization	Mouse
Su JL, Yang CY, Shih JY, Wei LH, Hsieh CY, Jeng YM, Wang MY, Yang PC, Kuo ML Knockdown of contactin-1 expression suppresses invasion and metastasis of lung adenocarcinoma. Cancer Res., 2006-03-01;66(5):2553-61. 2006-03-01 [PMID: 16510572] (Immunoprecipitation, Western Blot, Human)	Immunoprecipitation, Western Blot	Human
Shah BS, Rush AM, Liu S, Tyrrell L, Black JA, Dib-Hajj SD, Waxman SG Contactin associates with sodium channel Nav1.3 in native tissues and increases channel density at the cell surface. J. Neurosci., 2004-08-18;24(33):7387-99. 2004-08-18 [PMID: 15317864] (ICC, Western Blot, Human, Rat)	ICC, Western Blot	Human, Rat
Show All 21 Publications. Collapse Publications.

Catalog# & Formulation	Size	Price
Carrier Free AF904-SP

Gene Symbol	CNTN1
Uniprot	CAA79696()