P2Y12/P2RY12 Products

Description

P2Y12 is a Purinergic Receptor essential for the aggregation of blood platelets. There is evidence that mutations in P2Y12 cause a bleeding disorder, suggesting that knowledge of the P2Y12 receptor could advance the development of antiplatelet agents to treat cardiovascular diseases. Expression of P2Y12 has been reported in platelets, spinal cord, and many brain regions. ESTs for P2Y12 have been isolated from B-cell/lung/testis, brain, embryo, prostate, eye, kidney carcinoma, and colon carcinoma libraries. Cognate

Bioinformatics

Uniprot	AAH17898 Human NM_022788 Human Q9H244 Human Q9H244 Human
Product By Gene ID	64805
Alternate Names	ADPG-R Gi-coupled ADP receptor HORK3 HORK3P2Y12 platelet ADP receptor P2T(AC) P2Y purinoceptor 12 P2Y(AC) P2Y(ADP) P2Y(cyc) P2Y12ADP-glucose receptor purinergic receptor P2RY12 purinergic receptor P2Y, G-protein coupled, 12 putative G-protein coupled receptor SP1999G-protein coupled receptor SP1999

Research Areas for P2Y12/P2RY12

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GPCR