Species: Hu, Mu, Rt
Applications: WB
Host: Sheep Polyclonal
Species: Hu, Pm
Applications: WB, ELISA, Flow, ICC/IF
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
E3 ubiquitin ligase protein mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. It positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. It probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.
Bioinformatics
| Entrez |
Mouse
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
57534 |
| Alternate Names |
- DAPK-interacting protein 1
- DIP1
- DIP-1FLJ90676
- DKFZp686I0769
- DKFZp761M1710
- E3 ubiquitin-protein ligase MIB1
- EC 6.3.2
- EC 6.3.2.-
- KIAA1323
- MGC129660
- MIB
- Mind bomb homolog 1
- mindbomb homolog 1 (Drosophila)
- ubiquitin ligase mind bomb
- ubiquitin ligase protein MIB1
- Zinc finger ZZ type with ankyrin repeat domain protein 2
- ZZANK2MGC129659
- ZZZ6
|
Research Areas for Mind Bomb 1/MIB1
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