MAP1 Products

Description

MAP1 is a novel Bax-associating protein, named MAP-1 (Modulator of Apoptosis), mediates caspase-dependent apoptosis in mammalian cells when overexpressed. MAP-1 homodimerizes and associates with the proapoptotic Bax and the prosurvival Bcl-2 and Bcl-X(L) of the Bcl-2 family in vitro and in vivo in mammalian cells. These data suggest that MAP-1 mediates apoptosis through a mechanism that involves binding to Bax.

Bioinformatics

Entrez	64112 Human 64113 Mouse
Uniprot	AAH15044 Human AAH15044.1 Human NM_022151 Human NP_071434 Human NP_071434.2 Human Q96BY2 Human
Product By Gene ID	64112
Alternate Names	MAP1 MAP-1PNMA4Paraneoplastic antigen Ma4 modulator of apoptosis 1 paraneoplastic antigen like 4

Research Areas for MAP1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
MAP Kinase Signaling

Related MAP1 Blog Posts

Check out the latest blog posts on MAP1.

Role of RASSF1A in Death Receptor-Dependent Apoptosis Death-receptor apoptosis, or cell death, is essential for cellular growth regulation; its disruption is expressed in a variety of cancers. We at Novus Biologicals are one of the leading antibody suppliersfor apoptosis and cancer research groups, and t...    Read more.

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