Lipoprotein a Products

Description

The protein encoded by the Lipoprotein a gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence. (provided by RefSeq)

Bioinformatics

Entrez	4018 Human
Uniprot	EAW47596 Human P08519 Human
Product By Gene ID	4018
Alternate Names	AK38 antiangiogenic AK38 protein apo(a) Apo(a) APOA apolipoprotein(a) EC 3.4.21 EC 3.4.21.- EC 3.4.21.7 lipoprotein, Lp(a) LP lp(a) Lp(a)