LARS2 Products

Description

LARS2, also known as Probable leucine--tRNA ligase, mitochondrial, is a 903 amino acid protein that is 102 kDa, catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. Disease research is currently being performed with relation to LARS2 and rocky mountain spotted fever, specific phobia, spotted fever, phobia, lactic acidosis, mitochondrial encephalomyopathy, encephalomyopathy, neisseria meningitides, bipolar disorder, nasopharyngitis, pneumonia, schizophrenia, tuberculosis, malaria, and carcinoma. This protein has been shown to have interactions with 20 proteins including ICT1, SRPR, PMM2, NMNAT1, and NAF1 in tRNA aminoacylation, gene expression, mitochondrial tRNA aminoacylation, valine, leucine and isoleucine biosynthesis, and aminoacyl-tRNA biosynthesis pathways.

Bioinformatics

Entrez	23395 Human
Uniprot	NP_056155 Human NP_056155.1 Human
Product By Gene ID	23395
Alternate Names	EC 6.1.1 EC 6.1.1.4 KIAA0028leucine tRNA ligase 2, mitocondrial leucine translase Leucine--tRNA ligase leucyl-tRNA synthetase 2, mitochondrial LeuRS LEURS MGC26121 probable leucyl-tRNA synthetase, mitochondrial