HDAC1 Products

Description

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Bioinformatics

Entrez	297893 Rat 3065 Human 433759 Mouse
Uniprot	AAH00301 Human NM_004964 Human NP_001518 Human NP_004955 Human NP_004955.2 Human Q13547 Human
Product By Gene ID	3065
Alternate Names	EC 3.5.1.98 GON-10 HD1DKFZp686H12203 histone deacetylase 1 reduced potassium dependency, yeast homolog-like 1 RPD3L1RPD3

Research Areas for HDAC1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Breast Cancer
Cancer
Cell Cycle and Replication
Checkpoint signaling
Chromatin Research
Core ESC-Like Genes
DNA Double Strand Break Repair
DNA Repair
Epigenetics
Histone Deacetylases
Phospho-Specific
Stem Cell Markers

Related HDAC1 Blog Posts

Check out the latest blog posts on HDAC1.

The role of DNMT3A in development Epigenetics is the study of heritable change in gene activity despite alteration of the hosts DNA sequence.  Change in gene activity done independently of the DNA sequence is achieved by way of histone and DNA methylation.  Gene silencing in DNA ...    Read more.

The role of DNMT3B in the co-incidence of methyltransferase and tumor suppressor expression in malignancies Epigenetics is the process of heritable change in gene activity despite alteration of the hosts DNA sequence, essentially causing a change in a phenotype without a change in the genotype of a host. To change the gene sequence without interfering w...    Read more.

Read more HDAC1 related blogs.