GALNT9 Products

Description

GALNT9 encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. This gene is expressed specifically in the brain, with highest expression in the cerebellum. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez	50614 Human
Uniprot	NP_068580 Human NP_068580.2 Human Q9HCQ5 Human
Product By Gene ID	50614
Alternate Names	EC 2.4.1.41 GalNAc transferase 9 GALNAC-T9 GALNAC-T9 GalNAc-T9 GALNT9 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9) Polypeptide GalNAc transferase 9 polypeptide N-acetylgalactosaminyltransferase 9 pp-GaNTase 9 Protein-UDP acetylgalactosaminyltransferase 9 UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase 9 UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9 UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 9 (GalNAc-T9)