DHX58 Products

Description

Negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interactswith DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, inparticuliar HCV RNA. Binding occurs at blunt dsRNA termini

Bioinformatics

Entrez	79132 Human 80861 Mouse
Uniprot	AAH14949.1 Human EAW60798 Human NP_077024 Human NP_077024.2 Human Q96C10 Human
Product By Gene ID	79132
Alternate Names	D11LGP2E D11lgp2e D11LGP2probable ATP-dependent RNA helicase DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 EC 3.6.4.13 LGP2ortholog of mouse D11lgp2 Probable ATP-dependent helicase LGP2 Protein D11Lgp2 homolog RIG-I-like receptor LGP2 RLR RNA helicase LGP2

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