Species: Hu, Mu, Rt, Ca, Pm
Applications: WB, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, ICC/IF
Host: Goat Polyclonal
Species: Hu, Mu
Applications: WB, ELISA, Flow, ICC/IF, IHC, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
The protein encoded by the Cdk2 gene is a member of the Ser/Thr protein kinase family. This protein kinase is highlysimilar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of thecyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycleG1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex includingcyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its proteinphosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have beenreported. (provided by RefSeq)
Bioinformatics
Entrez |
Human Mouse Rat |
Uniprot |
Human Human |
Product By Gene ID |
1017 |
Alternate Names |
- cdc2-related protein kinase
- cell devision kinase 2
- Cell division protein kinase 2
- cyclin-dependent kinase 2
- EC 2.7.11
- EC 2.7.11.22
- p33 protein kinase
- p33(CDK2)
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