C1q Products

Description

C1q encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q.

Bioinformatics

Entrez	712 Human
Uniprot	AAH30153 Human AAH30153.1 Human NM_015991 Human NP_057075.1 Human P02745 Human P02747 Human
Product By Gene ID	712
Alternate Names	A chain complement component 1, q subcomponent, A chain complement component 1, q subcomponent, alpha polypeptide

Research Areas for C1q

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Immunology
Innate Immunity