Abeta 40 Products

Description

Amyloid beta-protein (Abeta) is associated with neuronal injury and death in Alzheimer's disease. The most common isoforms are of Amyloid beta are Abeta40 and Abeta42.

The Amyloid beta A4 protein (Abeta40) is the more common isoform and is the main components of amyloid plaques. Abeta-40 is produced by cleavage of the Amyloid Precursor Protein (APP) that occurs in the endoplasmic reticulum.

The Amyloid beta proteins function as a cell surface receptor and supports neurite growth, neuronal adhesion and axonogenesis on the surface of neurons. Amyloid betas are also involved in cell mobility functions and transcription regulation via various protein-protein interactions.

Abeta40 antibodies are useful tools for Alzheimer's studies and research on amyloid plaques.

Bioinformatics

Entrez	351 Human
Uniprot	P05067 Human
Product By Gene ID	351
Alternate Names	amyloid beta 40 Beta-amyloid protein 40

Research Areas for Abeta 40

Find related products by research area and learn more about each of the different research areas below.

Alzheimers Research
Apoptosis
Cell Cycle and Replication
Neurodegeneration
Neuronal Cell Markers
Neuroscience

Related Abeta 40 Blog Posts

Check out the latest blog posts on Abeta 40.

The C99 fragment of amyloid precursor protein (APP) Alzheimer’s Disease (AD) is a neurodegenerative disorder that is characterized by an abundance of the beta-amyloid peptide in the brain.  When AD was first discovered, it was determined that beta-amyloid was produced as a result of the prote...    Read more.

Amyloid beta and Methionine Sulfoxide Related to Abeta 42 Antibody and Abeta 40 Antibody By Eric NeeleyAlzheimer's disease is a devastating neurodegenerative illness characterized by the formation of plaques, tangles, and eventually synaptic loss. Amyloid beta (A beta ) is the processed form of the Amyloid precursor protein (APP), and whose ...    Read more.

Read more Abeta 40 related blogs.