| Immunogen | Glycated modified protein |
| Specificity | NB100-63095 recognizes a variety of advanced glycated end product (AGE) epitopes. Glycation is the post-translational modification of proteins, linking a reducing sugar to an amino group on a protein. AGEs are thought to be involved in structural and functional alterations of proteins observed in aging and diabetes. AGEs recognised by NB100-63095 include carboxymethyllysine and pentosidine. Increases in pentosidine levels are associated with aging, diabetes, cataracts, renal diseases, chronic rheumatoid arthritis, photaged skin and Alzheimers disease. Carboxymethyllysine is involved in uracemia. |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Goat |
| Purity | Unpurified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
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| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer | Whole antisera |
| Preservative | 0.09% Sodium Azide |
| Purity | Unpurified |
| Publication using NB100-63095 | Applications | Species |
|---|---|---|
| de Souza Pinto R, Castilho G, Paim BA. Inhibition of macrophage oxidative stress prevents the reduction of ABCA-1 transporter induced by advanced glycated albumin. Lipids 2012-05-01 [PMID: 22271422] (WB, Mouse) | WB | Mouse |
Secondary Antibodies |
Isotype Controls |
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